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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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AAA or AAA+ (ATPases Associated with diverse cellular Activities) proteins couple chemical energy provided by ATP hydrolysis to the remodeling or translocation of macromolecules. They are involved in a wide range of cellular processes, including DNA replication, protein degradation, membrane fusion, microtubule severing, peroxisome biogenesis, signal transduction and the regulation of gene expression.


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caseinolytic mitochondrial matrix peptidase proteolytic subunit Show summary »

katanin catalytic subunit A1 Show summary » More detailed page go icon to follow link

lon peptidase 1, mitochondrial Show summary »


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How to cite this family page

Database page citation:

AAA ATPases. Accessed on 20/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.