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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
AAA or AAA+ (ATPases Associated with diverse cellular Activities) proteins couple chemical energy provided by ATP hydrolysis to the remodeling or translocation of macromolecules. They are involved in a wide range of cellular processes, including DNA replication, protein degradation, membrane fusion, microtubule severing, peroxisome biogenesis, signal transduction and the regulation of gene expression.
katanin catalytic subunit A1 Show summary » More detailed page |
lon peptidase 1, mitochondrial Show summary » |
Database page citation:
AAA ATPases. Accessed on 19/03/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=933.
Concise Guide to PHARMACOLOGY citation:
Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.