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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
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More detailed introduction
This is a family of glycoproteins that contain a classical Ig antibody constant domain-like tertiary structure. This so-called C1-set domain is present in immunoglobulin heavy and light chains, proteins of the MHC class I and II complex, and a number of T cell receptors.
FcRn (Fc fragment of IgG receptor and transporter)
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Database page citation:
Immunoglobulin C1-set domain-containing proteins. Accessed on 03/12/2023. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=985.
Concise Guide to PHARMACOLOGY citation:
Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. Br J Pharmacol. 178 Suppl 1:S1-S26.