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Immunoglobulin C1-set domain-containing proteins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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This is a family of glycoproteins that contain a classical Ig antibody constant domain-like tertiary structure. This so-called C1-set domain is present in immunoglobulin heavy and light chains, proteins of the MHC class I and II complex, and a number of T cell receptors.


FcRn (Fc fragment of IgG receptor and transporter) Show summary » More detailed page

How to cite this family page

Database page citation:

Immunoglobulin C1-set domain-containing proteins. Accessed on 28/09/2020. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. Br J Pharmacol. 176 Issue S1: S1-S20.