abivertinib [Ligand Id: 10044] activity data from GtoPdb

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  • epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533]
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  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
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  • Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533]
GtoPdb In a biochemical assay. - 8.11 pIC50 7.68 nM IC50 Mol. Cancer Ther. (2016) 15: 2586-2597 [PMID:27573423]
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb In a biochemical assay. - 9.4 pIC50 0.4 nM IC50 Mol. Cancer Ther. (2016) 15: 2586-2597 [PMID:27573423]
Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
GtoPdb In a biochemical assay. - 10.05 pIC50 0.09 nM IC50 Mol. Cancer Ther. (2016) 15: 2586-2597 [PMID:27573423]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.