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The IUPHAR/BPS Guide to PHARMACOLOGY complete ligand list


All ligands in the database which are currently, or have been in the past, approved for human clinical use by a regulatory agency.

A  B  C  D  E  F  G  H  I  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z 

Ligand name ID Synonyms
A Back to top
abaloparatide 8299 BA058, Tymlos®
abarelix 1188 Plenaxis®, PPI 149, R 3827
abatacept 6891 BMS-188667, CTLA4-IgG4m, Orencia®, RG-1046, RG-2077
abciximab 6584 7E3 antibody, antiGPIIBIIIa, C7E3, ReoPro®
abemaciclib 7382 CS-1230, HY-16297A, LY 2835219, LY2835219, Verzenio®, Verzenios®
abiraterone acetate 9288 Yonsa®, Zytiga®
acalabrutinib 8912 ACP-196, Calquence®, Example 6 [US20140155385 A1]
acamprosate 7106 Campral®
acarbose 6791 BAY-G 5421, BAY-G-5421, Glucobay®, Precose®
acebutolol 7107 IL-17803A, Sectral®
acenocoumarol 9015 Sinthrome®, Sintrom®
acetazolamide 6792 Diamox®
acetohexamide 6793 Dymelor®
acetylcysteine 10945 Ilube® (eye drops), N-A-C Sustain®, N-Acetyl-cysteine, N-Acetyl-L-cysteine, NAC, Parvolex®
acetyldigitoxin 6794 acetyldiginatin, Acylanid®, alpha-acetyldigitoxin
aciclovir 4829 acyclovir, Zovirax®
acipimox 1596 Olbetam®
acitretin 7598 Ro-101670000, Soriatane®
aclidinium 7449 LAS W-330, LAS-34273, Tudorza Pressair®
ACTH  {Sp: Human} 3633 Acthar®, adrenocorticotropic hormone (1-39), corticotropin
adalimumab 4860 D2E7, FKB327, Humira®
adapalene 5429 Differin®
adenosine 2844 Adenocard®, Adenoscan®
adomeglivant 9479 LY2409021
(-)-adrenaline 479 adrenalin, Auvi-Q®, Epipen®, l-adrenaline, L-epinephrine, levoepinephrine
afamelanotide 1324 α-NDP-MSH, [Nle4,dPhe7]α-MSH, CUV-1647, CUV1647, NDP-MSH, Scenesse®
afatinib 5667 BIBW2992, Gilotrif®
aflibercept 6786 AVE0005, Eylea®, VEGF Trap, Zaltrap®, ziv-aflibercept
agomelatine 198 S20098, Thymanax®, Valdoxan®
ajmalicine 8746 delta-yohimbine, raubasine, rauvasan, rauwolfia alkaloid
albiglutide 7386 Eperzan®, GSK716155, Tanzeum®
alcaftadine 7587 Lastacaft®, R-89674
alectinib 7739 AF802, Alecensa®, CH5424802
alefacept 6787 Amevive®, BG 9273, BG 9712, BG-9273, BG-9712, Lfa3Tip
alemtuzumab 6770 campath 1H, Campath®, campath-1H, Lemtrada®
alendronate 3141 ABDP, BPH 1, Fosamax®, MK-217
alfentanil 7108 Alfenta®, R-39209, Rapifen®
alfuzosin 7109 SL-77499-10, SL-7749910, Uroxatral®
alglucosidase alfa 7561 Lumizyme®, Myozyme®, rhGAA
alimemazine 7237 Nedeltran®, trimeprazine
alirocumab 6744 Praluent®, REGN727, SAR-236553, SAR236553
aliskiren 4812 CGP-060536B, SPP100, Tekturna®
alitretinoin 2645 9-cis-retinoic acid, Panretin®, Toctino®
allopurinol 6795 Aloprim®, BW-56-158, BW-56158, Zyloprim®
almotriptan 7110 Almogran®, Axert®, LAS-31416, PNU-180638E
alogliptin 6319 Nesina®, SYR-322, Vipidia®
alosetron 2296 GR68755, Lotronex®
alpelisib 7955 BYL 719, BYL-719, NVP-BYL719, Piqray®
alpha-methyltyrosine 6956 Demser®, metyrosine, MK-781
alpha1-proteinase inhibitor 7487 A1AT, A1PI, alpha 1-antitrypsin, Aralast®, Prolastin®, serum trypsin inhibitor
alprazolam 7111 Niravam®, U-31889, Xanax®
alprenolol 563 Atenenol®
AlprolixTM 7373
altretamine 7112 Hexalen®
alvimopan 7471 ADL 8-2698, Entereg®
amantadine 4128 ADS-5102, Gocovri®, Symadine®, Symmetrel®
ambrisentan 3951 Letairis®
ambroxol 10692
amcinonide 7060 CL-34699, Cyclocort®
amfenac 7565 AHR-5850D, Fenazox® (Japan)
amifampridine 8032 3,4-DAP, 3,4-diaminopyridine, Firdapse®, Ruzurgi®, Zenas®
amikacin 10894 Amikin®, AMK, BB-K8
amiloride 2421 amiloride HCl, Midamor®
6-aminocaproic acid 6574 ε-aminocaproic acid, Amicar®, EACA
aminoglutethimide 7054 Cytadren®
aminohippuric acid 4810 PAH, Aminohippurate Sodium®, p-aminohippurate, p-aminohippuric acid, PAH
5-aminolevulinic acid 4784 5-aminolevulinate, Ameluz®, D-aminolevulinic acid, Gliolan®, Levulan®
amiodarone 2566 amiodarone hydrochloride, Cordarone®
amisulpride 963 (±)-amisulpride, Barhemsys®
amitriptyline 200 amitryptiline, Elavil®, Endep®
amlexanox 7113 AA-673, Amlexanox®, Aphthasol®, CHX-3673
amlodipine 6981 amlodipine besylate, amlodipine maleate, Copalia® (amlodipine + valsartan), Katerzia® (amlodipine oral suspension, 1 mg/mL), Norvasc®, UK-4834011
amodiaquine 10018 Alphaquine®, Amdaquine®, Amoquin®, Camoquin®, Flavoquine®
amoxapine 201 amoxipine, Asendin®
amoxicillin 10895 Amoxil®, BRL-2333, co-amoxiclav (amoxicillin + clavulanic acid), Moxatag®, NSC-277174, Trimox®
amphetamine 4804 (±)-amphetamine, Amphetamine Sulfate®, DL-amphetamine
ampicillin 10896 aminobenzylpenicillin, KS-R1, Penbritin®, Polycillin, Principen®
anagrelide 7114 Agrylin®, BL-4162a, Xagrid®
anakinra 6972 antril, Kineret®
anastrozole 5137 Arimidex®
andexanet alfa 7576 Andexxa®, coagulation factor Xa (recombinant), inactivated-zhzo, Ondexxya®, PRT064445, PRT4445, r-antidote
angiotensin II  {Sp: Human, Mouse, Rat} 2504 ang II, Giapreza®
anileridine 7115 Leritine®
aniracetam 4133
anisindione 6960 Miradon®
antazoline 7116
apalutamide 9043 ARN-509, ARN509, Erleada®, JNJ-56021927
apatinib 7648 YN968D1
apixaban 6390 BMS-562247, Eliquis®
apomorphine 33 Apokyn®, Ixense®, Kynmobi® (sublingual film), Uprima®
apraclonidine 7117 AL-02145, Iopidine®
apremilast 7372 CC-10004, Otezla®
aprepitant 3490 Emend®
aprotinin  {Sp: Bovine} 6570 basic protease inhibitor (BPI), BPTI, pancreatic trypsin inhibitor, Trasylol®
arformoterol 7479 Brovana®, YM-08316
argatroban 6385 DK-7419, GN-1600, Gn1600, MCI-9038, MD-805
aripiprazole 34 Abilify®, Aripiprex®, Aristada® (aripiprazole lauroxil), OPC 14597, OPC-14597
artemether 9955 β-artemether, beta-artemether
artenimol 9957 DHA, dihydroartemisinin, GNF-Pf-5634
artesunate 9956
asenapine 22 ORG-5222, ORG5222, Saphris®, Secuado® (transdermal asenapine), Sycrest®
aspirin 4139 Acetophen®, acetylsalicylic acid, Aspirin®
astemizole 2603 Hismanal®
asunaprevir 10882 BMS-650032, BMS650032, compound 24 [PMID: 24564672], Sunvepra™
ataluren 7341 PTC124
atenolol 548 Myocord®, Normiten®, Tenormin®
atezolizumab 7990 MPDL3280A, Tecentriq®
atomoxetine 7118 LY-139603, Strattera®
atorvastatin 2949 Lipitor®
atosiban 2213 Antocin®, d[D-Tyr(Et)2,Thr4,Orn8]vasotocin, d[D-Tyr(Et)2,Thr4]OVT, ORF22164, RWJ 22164, Tractocile®
atovaquone 9695 566C80, Mepron®, Wellvone®
atracurium 9537 atracurium besilate, atracurium dibesylate, BW 33A, Tracrium®
atropine 320 Atropen®, hyoscyamine
auranofin 6306 Ridaura®, SK&F-39162, SK-39162
avanafil 7448 Spedra®, Stendra®, TA-1790
avapritinib 10368 Ayvakit®, BLU-285, BLU285
avatrombopag 9953 AKR-501, Doptelet®, E5501, YM477
avelumab 8735 Bavencio®, MSB-0010718C, MSB0010718C
avibactam 10761 AVI, NXL 104, NXL-104, NXL104
aviptadil 10891 Invicorp® (aviptadil + phentolamine), Vasoactive intestinal octacosapeptide
axitinib 5659 AG 013736, AG-013736, AG013736, Inlyta®
azacitidine 6796 5-AZAC, 5-azacytidine, ladakamycin, U-18496, Vidaza®
azasetron 2285 Y-25130
azatadine 7119 Optimine®, SCH-10649
azathioprine 7120 Azasan®, BW-57-322, Imuran®
azelaic acid 7484 Azelex®, Finacea®, ZK-62498
azelastine 7121 A-5610, Astelin®, E-0659, Rhinolast®, W-2979M
azilsartan medoxomil 6900 Edarbi®, TAK 491
azithromycin 6510
aztreonam 10763 Azactam®, Cayston®, SQ 26776, SQ-26776, SQ26776
 
B Back to top
baclofen 1084 Baclon®, Kemstro®, Lioresal®
bambuterol 6601 Bambec®, Oxeol®
baricitinib 7792 INCB-028050, INCB028050, LY-3009104, LY3009104, Olumiant®
basiliximab 6879 CHI-621, L04AC02, SDZ-CHI-621, Simulect®
bazedoxifene 7355 Conbriza®, TSE-424, Viviant®, WAY-140424
beclometasone 7059 beclomethasone, SCH-18020W
beclometasone dipropionate 5894 beclomethasone dipropionate, Beconase®, Qnasl®, Vancenase®
belatacept 6892 BMS-224818, LEA29Y, Nulojix®
belimumab 6887 Benlysta®, hBlySmAb-1.1, LimphoStat-B, lymphostat-B
belinostat 7496 Beleodaq®, PXD-101, PXD101
bempedoic acid 8321 ESP-55016, ETC-1002, Nexletol®
benazepril 6374 CGS-14824A, Lotensin®
benazeprilat 6375 CGS-14831
bendamustine 7478 Levact®, SDX-105, Treanda®
bendroflumethiazide 7122 Aprinox®, Naturetin®
benidipine 10159 Coniel®
benperidol 9215 Anquil®, MCN-JR-4584, R-4584
benralizumab 7674 BIW-8405, Fasenra®, KHK4563, MEDI-563
benserazide 5150 Madopar®, Ro 4-4602, serazide
benzatropine 7601 benztropine, benztropine mesylate, Cogentin®
benzonatate 7611 Tessalon®, Zonatuss®
benzquinamide 7124 P-2647, Quantril®
benzthiazide 7125 Aquatag®, Fovane®
bepotastine 7466 Talion®, TAU-284
bepridil 2337 CERM-1978, Vascor®
betamethasone 7061 SCH-4831
betanidine 7618 bethanidine, BW-467-C-60, Tenathan®
betaxolol 549 betaxolol HCl, Betoptic®, Kerlone®, SL-75212-10
betazole 7126 ametazole, Histalog®
bethanechol 297 Duvoid®, Urecholine®
betrixaban 9602 Bevyxxa®, compound 11 [PMID: 19297154], PRT-054021, PRT054021
bevacizumab 6771 Avastin®, rhuMAb-VEGF
bexarotene 2807 LGD1069, Targretin®, Targrexin®
bezafibrate 2668 Bezalip®
bicalutamide 2863 Calutide®, Casodex®
bimatoprost 1958 AGN 192024, LS-181817, Lumigan®
binimetinib 7921 ARRY 162, ARRY-162, ARRY-438162, MEK-162, MEK162, Mektovi®
biperiden 7128 Akineton®, biperiden HCl, biperiden lactate
bisoprolol 7129 CL-297939, EMD-33512, Zebeta®
bivalirudin 6470 Angiomax®
blinatumomab 7384 Blincyto®, bscCD19xCD3, MEDI-538, MT-103, MT103
blonanserin 7670 AD 5423, AD-5423, Lonasen®
boceprevir 7876 EBP-520, EBP520, SCH-503034, SCH503034, Victrelis®
bortezomib 6391 peptide boronate, PS-341, Velcade®
bosentan 3494 RO 47-0203, Tracleer®
bosutinib 5710 Bosulif®, SK 606, SK-606, SKI 606
brain natriuretic peptide  {Sp: Human} 4890 BNP, BNP(1-32), BNP-32, brain natriuretic peptide 32, Natrecor®
bremelanotide 10408 PT-141, PT141, Vyleesi®
brentuximab vedotin 6772 Adcetris®, anti-CD30 ADC SGN-35, SGN 35
bretylium 7130 ASL-603, bretylium tosylate, Bretylol®
brexpiprazole 7672 OPC 34712, OPC-34712, Rxulti®
brigatinib 7741 Alunbrig®, AP-26113, AP26113, compound 11q [PMID: 27144831]
brimonidine 520 Alphagan®, Lumify®, Mirvaso®, UK14,304, UK14304
brinzolamide 6797 AL-4862, Azopt®
brivaracetam 9041 2-(2-oxo-4-propylpyrrolidin-1-yl)butanamide, Briviact®, compound 83α, UCB 34714, UCB-34714, UCB34714
brodalumab 7540 AMG-827, AMG827, Kyntheum®, Lumicef®, Siliq®
brolucizumab 8713 Beovu®, brolucizumab-dbll, ESBA-1008, ESBA1008, RTH258
bromfenac 7131 AHR-10282B, Bromday®, Prolensa®, Xibrom®
bromocriptine 35 2-bromoergocryptine, bromocryptine, CB-154, Parlodel®
bromodiphenhydramine 7132 Ambodryl®
brompheniramine 7133 Bromfed®, brompheniramine maleate, Dimetapp®
buclizine 7134 UCB-4445
budesonide 7434 Entocort®, Jorveza®, Pulmicort®, S-1320, Uceris®
bufexamac 7498 CP-1044-J3, Paraderm®, Parfenac®
bumetanide 4837 Bumex®, Burinex®, PF 1593, Ro 10-6338
bupivacaine 2397 DL-Bupivacaine, Marcain®, Sensorcaine®, W-7
bupranolol 550 Betadrenol®, BRN 2272923, Ophtorenin®, SK&F 16805-A
buprenorphine 1670 Buprenex®, Buvidal®, CAM2038, Sixmo® (buprenorphine hydrochloride), Temgesic®
bupropion 7135 amfebutamone, BW-323, Wellbutrin®, Zyban®
burosumab 9292 burosumab-twza, Crysvita®, KRN-23, KRN23, N5KG1_C10_LH, UX-023, UX023
buserelin 3860 buserelin acetate, HOE 766, HOE 766A, ICI 123215, Metrelef®, Suprefact®
buspirone 36 Buspar®, MJ-9022-1
busulfan 7136 Busulfex IV®, Myleran®
butabarbital 7137 Butisol®
butalbital 7138 alisobumal, allylbarbituric acid, itobarbital, tetrallobarbital
butorphanol 7591 butorphanol tartrate, LEVO-BC-2627
 
C Back to top
cabazitaxel 6798 Jevanta®, taxoid XRP6258, TXD 258, XRP-6258
cabergoline 37 Cabaser®, Caberlin®
cabozantinib 5887 BMS907351, Cabometyx®, Cometriq®, XL-184, XL184
caffeine 407 Peyona®
calcifediol 6921 25-hydroxyvitamin D3, calcidiol, Calderol, Ryaldee®, U-32070E
calcipotriol 2778 Dovonex®, MC903
calcitonin  {Sp: Human} 685 CT, LS-173874, thyrocalcitonin
calcitonin (salmon) 6973 CT (salmon), Miacalcin®
camostat 6432 ONO-3403
camrelizumab 9758 INCSHR1210, SHR-1210
canagliflozin 4582 Invokana®, JNJ-28431754, TA-7284
canakinumab 6773 ACZ 885, ACZ885, Ilaris®
candesartan 587 CV-11974, TCV-116 (prodrug)
cangrelor 1776 AR-C69931MX, ARL69931, Kengreal®, Kengrexal®
cannabidiol 4150 CBD, Epidiolex®, GWP42003-P
capecitabine 6799 Ro-09-1978-000, Ro-091978000, Xeloda®
caplacizumab 9123 ALX-0081, anti-vWF Nanobody, Cablivi®, caplacizumab-yhdp
capmatinib 7904 INC280, INCB28060, Tabrecta®
capromab 6878 capromab pendetide, CYT-351, CYT-356, Indium In 111 capromab, ProstaScint®
capsaicin 2486 Qutenza®
captopril 5158 Capoten®, SQ-14225
carazolol 569 BM-51052, conducton, corazolol
carbachol 298 Carbastat®, Carboptic®
carbamazepine 5339 calepsin, Carnexiv®, Tegretol®
carbenicillin 10768 BRL-2064, BRL2064, carboxybenzylpenicillin, CBPC, CP 15639-2, CP-156392, Pyopen®
carbidopa 5159 Duodopa®, Lodosyn®
carbinoxamine 7139 carbinoxamine maleate, Clistin®
carboplatin 7624 JM-8, Paraplatin®
carfilzomib 7420 Kyprolis®, PR-171
carglumic acid 7458 N-carbamylglutamate, Carbaglu®, OE-312
cariprazine 7671 Reagila®, RGH 188, RGH-188, Vraylar®
carisoprodol 7610 Soma®
carmustine 6800 BiCNU®, Carustine®
carphenazine 7140 Proketazine®, WY-2445
carprofen 7141 Ro-205720000
carteolol 7142 ABBOTT-43326, Cartrol®, Ocupress®, OPC-1085
carvedilol 551 Coreg®, DQ 2466, Eucardic®, SKF 105517
catequentinib 9601 AL-3818, AL3818, anlotinib
catumaxomab 7385 L01XC09, Removab®
cefaclor 10897 Ceclor®, Lilly 99638, Raniclor®
cefadroxil 4831 Duricef®
cefepime