desoximetasone [Ligand Id: 7067] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1766 (J83.644C, R-2113, Stiedex lpn, HOE 304, A-41304, R 2113, Topicort, Stiedex lp, A-41-304, HOE-304, Stiedex, Desoximetasone, Topicort lp)
1 CHEMBL1766_lig_chart_1 Glucocorticoid receptor Human
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  • Progesterone receptor in Bovine [ChEMBL: CHEMBL1909044] [UniProtKB: Q690N0]
  • This target only has 1 pki data point
  • 7.96
2 CHEMBL1766_lig_chart_2 Progesterone receptor Bovine
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Glucocorticoid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2034] [GtoPdb: 625] [UniProtKB: P04150]
GtoPdb - - 8.93 pKi 1.17 nM Ki National Toxicology Program: Dept of Health and Human Services.. DrugMatrix
ChEMBL DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) B 8.93 pKi 1.17 nM Ki DrugMatrix in vitro pharmacology data
ChEMBL DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) B 8.59 pIC50 2.57 nM IC50 DrugMatrix in vitro pharmacology data
Progesterone receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1909044] [UniProtKB: Q690N0]
ChEMBL DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) B 7.96 pKi 11 nM Ki DrugMatrix in vitro pharmacology data
ChEMBL DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) B 7.08 pIC50 84 nM IC50 DrugMatrix in vitro pharmacology data

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]