amuvatinib   Click here for help

GtoPdb Ligand ID: 7932

Synonyms: MP 470 | MP-470 | MP470
Compound class: Synthetic organic
Comment: Amuvatinib is an orally bioavailable, multitargeted receptor tyrosine kinase inhibitor. Some bioactivity data may be associated with the hydrochloride salt (PubChem CID 67254077).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 107.98
Molecular weight 447.14
XLogP 3.86
No. Lipinski's rules broken 0
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Canonical SMILES S=C(N1CCN(CC1)c1ncnc2c1oc1c2cccc1)NCc1ccc2c(c1)OCO2
Isomeric SMILES S=C(N1CCN(CC1)c1ncnc2c1oc1c2cccc1)NCc1ccc2c(c1)OCO2
InChI InChI=1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,24,32)
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
9278 amuvatinib
Synonyms Click here for help
MP 470 | MP-470 | MP470
Database Links Click here for help
CAS Registry No. 850879-09-3
ChEMBL Ligand CHEMBL2103851
GtoPdb PubChem SID 249565615
PubChem CID 11282283
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UniChem Compound Search for chemical match using the InChIKey FOFDIMHVKGYHRU-UHFFFAOYSA-N
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