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Compound class: Synthetic organic
Comment: HTH-01-015 is a selective inhibitor of the protein kinase, NUAK family SNF1-like kinase 1 (NUAK1) .
N.B. compare to WZ4003 which inhibits both NUAK1 and NUAK2. HTH-01-015 and WZ4003 can be used as chemical probes to delineate the biological roles of the NUAK kinases.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Synthetic organic|
|CAS Registry No.||1613724-42-7 (source: PubChem)|
|GtoPdb PubChem SID||310264757|
|Search Google for chemical match using the InChIKey||CHSDJDLAKKAWCI-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||CHSDJDLAKKAWCI|
|UniChem Compound Search for chemical match using the InChIKey||CHSDJDLAKKAWCI-UHFFFAOYSA-N|
|UniChem Connectivity Search for chemical match using the InChIKey||CHSDJDLAKKAWCI-UHFFFAOYSA-N|
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HTH 01-015 (links to external site)
Cat. No. 5622