drospirenone   Click here for help

GtoPdb Ligand ID: 2874

Synonyms: dihydrospirorenone | Slynd® | Yasmin® | ZK30595
Approved drug
drospirenone is an approved drug
Compound class: Synthetic organic
Comment: Drospirenone is a synthetic analogue of spironolactone, that has a similar pharmacological profile to endogenous progesterone. As a contraceptive agent it is used for its progestin-like activity, but it also has anti-androgen and anti-mineralocorticoid properties.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 43.37
Molecular weight 366.22
XLogP 4.35
No. Lipinski's rules broken 0
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Canonical SMILES O=C1CCC2(C(=C1)C1CC1C1C2CCC2(C1C1CC1C12CCC(=O)O1)C)C
Isomeric SMILES O=C1CC[C@]2(C(=C1)[C@@H]1C[C@@H]1[C@@H]1[C@@H]2CC[C@]2([C@H]1[C@@H]1C[C@@H]1[C@]12CCC(=O)O1)C)C
InChI InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
6519 drospirenone
Synonyms Click here for help
dihydrospirorenone | Slynd® | Yasmin® | ZK30595
Database Links Click here for help
CAS Registry No. 67392-87-4
ChEMBL Ligand CHEMBL1509
DrugBank Ligand DB01395
DrugCentral Ligand 968
GtoPdb PubChem SID 135650211
PubChem CID 68873
Search Google for chemical match using the InChIKey METQSPRSQINEEU-HXCATZOESA-N
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UniChem Compound Search for chemical match using the InChIKey METQSPRSQINEEU-HXCATZOESA-N
UniChem Connectivity Search for chemical match using the InChIKey METQSPRSQINEEU-HXCATZOESA-N
Wikipedia Drospirenone