gatifloxacin   Click here for help

GtoPdb Ligand ID: 10816

Synonyms: AM-1155 | AM1155 | Gatiflo® | GTFX | Tequin® | Zymar®
Approved drug
gatifloxacin is an approved drug
Compound class: Synthetic organic
Comment: Gatifloxacin is a synthetic fourth-generation fluoroquinolone antibacterial with broad-spectrum activity against Gram-negative and Gram-positive pathogens.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 83.8
Molecular weight 375.16
XLogP 4.21
No. Lipinski's rules broken 0
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Canonical SMILES COc1c(N2CCNC(C2)C)c(F)cc2c1n(cc(c2=O)C(=O)O)C1CC1
Isomeric SMILES COc1c(N2CCNC(C2)C)c(F)cc2c1n(cc(c2=O)C(=O)O)C1CC1
InChI InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
Withdrawn drug? Yes
IUPAC Name Click here for help
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
International Nonproprietary Names Click here for help
INN number INN
7423 gatifloxacin
Synonyms Click here for help
AM-1155 | AM1155 | Gatiflo® | GTFX | Tequin® | Zymar®
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Gatifloxacin
Other databases
CAS Registry No. 112811-59-3 (source: WHO INN record)
DrugCentral Ligand 1280
GtoPdb PubChem SID 405560257
PubChem CID 5379
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UniChem Compound Search for chemical match using the InChIKey XUBOMFCQGDBHNK-UHFFFAOYSA-N
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