BMS-986235   

GtoPdb Ligand ID: 11024

Synonyms: BMS986235 | compound 13c [PMID: 32407089] | LAR-1219 | LAR1219
Compound class: Synthetic organic
Comment: BMS-986235 (LAR-1219) is a selective formyl peptide receptor 2 (FPR2) agonist [1]. It is being proposed as a preventative heart failure agent, via promoting resolution of inflammation.
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 79.46
Molecular weight 361.12
XLogP 2.38
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES COc1cc(F)c(c(c1)F)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccccc1
Isomeric SMILES COc1cc(F)c(c(c1)F)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccccc1
InChI InChI=1S/C18H17F2N3O3/c1-26-11-7-13(19)15(14(20)8-11)12-9-21-17(24)16(12)23-18(25)22-10-5-3-2-4-6-10/h2-8,12,16H,9H2,1H3,(H,21,24)(H2,22,23,25)/t12-,16-/m0/s1
InChI Key FJZNNKJZHQFMCK-LRDDRELGSA-N
Classification
Compound class Synthetic organic
IUPAC Name
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-phenylurea
Synonyms
BMS986235 | compound 13c [PMID: 32407089] | LAR-1219 | LAR1219
Database Links
GtoPdb PubChem SID 405560465
PubChem CID 122583088
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