acesulfame [Ligand Id: 12460] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL176687 (Acesulfame) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| carbonic anhydrase 2/Carbonic anhydrase II in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL205] [GtoPdb: 3092] [UniProtKB: P00918] | ||||||||
| ChEMBL | Binding affinity to carbonic anhydrase 2 (unknown origin) | B | 4.7 | pKi | >20000 | nM | Ki | ACS Med Chem Lett (2018) 9: 657-661 [PMID:30034596] |
| carbonic anhydrase 9/Carbonic anhydrase IX in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3594] [GtoPdb: 3055] [UniProtKB: Q16790] | ||||||||
| ChEMBL | Binding affinity to carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 (DE3) | B | 5.62 | pKi | 2400 | nM | Ki | ACS Med Chem Lett (2018) 9: 657-661 [PMID:30034596] |
| TAS2R31 in Human [GtoPdb: 674] [UniProtKB: P59538] | ||||||||
| GtoPdb | - | - | 2.6 | pEC50 | 2500000 | nM | EC50 | J Neurosci (2004) 24: 10260-5 [PMID:15537898] |
| TAS2R43 in Human [GtoPdb: 678] [UniProtKB: P59537] | ||||||||
| GtoPdb | - | - | 2.51 | pEC50 | 3100000 | nM | EC50 | J Neurosci (2004) 24: 10260-5 [PMID:15537898] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
