compound 23 [PMID: 35816678] [Ligand Id: 12059] activity data from GtoPdb

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  • protein kinase C delta in Human [GtoPdb: 1485] [UniProtKB: Q05655]
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  • Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
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  • ribosomal protein S6 kinase A5 in Human [GtoPdb: 1523] [UniProtKB: O75582]
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  • ribosomal protein S6 kinase A4 in Human [GtoPdb: 1524] [UniProtKB: O75676]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
protein kinase C delta in Human [GtoPdb: 1485] [UniProtKB: Q05655]
GtoPdb - - 7.15 pIC50 71 nM IC50 J Med Chem (2022) 65: 9819-9845 [PMID:35816678]
Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
GtoPdb - - 8.52 pIC50 <3 nM IC50 J Med Chem (2022) 65: 9819-9845 [PMID:35816678]
ribosomal protein S6 kinase A5 in Human [GtoPdb: 1523] [UniProtKB: O75582]
GtoPdb - - 6.84 pIC50 143 nM IC50 J Med Chem (2022) 65: 9819-9845 [PMID:35816678]
ribosomal protein S6 kinase A4 in Human [GtoPdb: 1524] [UniProtKB: O75676]
GtoPdb - - 7.07 pIC50 85 nM IC50 J Med Chem (2022) 65: 9819-9845 [PMID:35816678]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.