bupranolol   Click here for help

GtoPdb Ligand ID: 550

Synonyms: Betadrenol® | BRN 2272923 | Ophtorenin® | SK&F 16805-A
Approved drug
bupranolol is an approved drug
Compound class: Synthetic organic
Comment: Bupranolol is a β-adrenoceptor antagonist (beta blocker) with a similar potency to propranolol.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 41.49
Molecular weight 271.13
XLogP 3.24
No. Lipinski's rules broken 0
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Canonical SMILES OC(COc1cc(C)ccc1Cl)CNC(C)(C)C
Isomeric SMILES OC(COc1cc(C)ccc1Cl)CNC(C)(C)C
InChI InChI=1S/C14H22ClNO2/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4/h5-7,11,16-17H,8-9H2,1-4H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
3166 bupranolol
Synonyms Click here for help
Betadrenol® | BRN 2272923 | Ophtorenin® | SK&F 16805-A
Database Links Click here for help
Specialist databases
GPCRdb Ligand bupranolol
Reactome Drug Reactome logo R-ALL-9611002
Reactome Reaction Reactome logo R-HSA-9609310
Other databases
BindingDB Ligand 25765
CAS Registry No. 14556-46-8 (source: Scifinder)
ChEMBL Ligand CHEMBL305380
DrugBank Ligand DB08808
DrugCentral Ligand 433
GtoPdb PubChem SID 135650033
PubChem CID 2475
Search Google for chemical match using the InChIKey HQIRNZOQPUAHHV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HQIRNZOQPUAHHV
Search PubMed clinical trials bupranolol
Search PubMed titles bupranolol
Search PubMed titles/abstracts bupranolol
UniChem Compound Search for chemical match using the InChIKey HQIRNZOQPUAHHV-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey HQIRNZOQPUAHHV-UHFFFAOYSA-N
Wikipedia Bupranolol