iodoaminopotentidine [Ligand Id: 1232] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL72193 |
|---|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Histamine H2 receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2882] [UniProtKB: P47747] | ||||||||
| ChEMBL | Histamine H2 receptor antagonistic activity at a concentration of 1 uM on the isolated guinea pig right atrium. | F | 7.56 | pKd | 27.54 | nM | Kd | J Med Chem (1992) 35: 2231-2238 [PMID:1613748] |
| ChEMBL | Inhibition of [125I]APT binding to histamine H2 receptor in guinea pig cerebral membranes. | B | 9.15 | pKi | 0.71 | nM | Ki | J Med Chem (1992) 35: 2231-2238 [PMID:1613748] |
| H2 receptor in Rat [GtoPdb: 263] [UniProtKB: P25102] | ||||||||
| GtoPdb | - | - | 9.2 | pKi | - | - | - | Br J Pharmacol (1997) 122: 867-74 [PMID:9384502] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
