bilobalide [Ligand Id: 2366] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL1318117
  • 5-HT3AB in Human [GtoPdb: 378]
There should be some charts here, you may need to enable JavaScript!
  • 5-HT3A in Human [GtoPdb: 379]
There should be some charts here, you may need to enable JavaScript!
  • glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
There should be some charts here, you may need to enable JavaScript!
  • glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
There should be some charts here, you may need to enable JavaScript!
  • glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT3AB in Human [GtoPdb: 378]
GtoPdb - - 2.51 pIC50 3100000 nM IC50 Neuropharmacology (2011) 60: 488-95 [PMID:21059362]
5-HT3A in Human [GtoPdb: 379]
GtoPdb - - 3.33 pIC50 470000 nM IC50 Mol. Pharmacol. (2011) 80: 183-90 [PMID:21505038]
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
GtoPdb - - 4.7 pIC50 20000 nM IC50
glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
GtoPdb - - 5.1 pIC50 8000 nM IC50
glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
GtoPdb - - 3.7 pIC50 204000 nM IC50
GtoPdb - - 4.3 pIC50 50000 nM IC50

ChEMBL data shown on this page come from version 26:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]