bilobalide [Ligand Id: 2366] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1318117
  • 5-HT3AB in Human [GtoPdb: 378]
  • This target only has 0 pki data point
  • 0
1 CHEMBL1318117_lig_chart_1 5-HT3AB Human
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  • 5-HT3A in Human [GtoPdb: 379]
  • This target only has 0 pki data point
  • 0
2 CHEMBL1318117_lig_chart_2 5-HT3A Human
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  • glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
  • This target only has 0 pki data point
  • 0
3 CHEMBL1318117_lig_chart_3 glycine receptor α1 subunit Human
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  • glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
  • This target only has 0 pki data point
  • 0
4 CHEMBL1318117_lig_chart_4 glycine receptor α2 subunit Human
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  • glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
  • This target only has 0 pki data point
  • 0
5 CHEMBL1318117_lig_chart_5 glycine receptor β subunit Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT3AB in Human [GtoPdb: 378]
GtoPdb - - 2.51 pIC50 3100000 nM IC50 Neuropharmacology (2011) 60: 488-95 [PMID:21059362]
5-HT3A in Human [GtoPdb: 379]
GtoPdb - - 3.33 pIC50 470000 nM IC50 Mol Pharmacol (2011) 80: 183-90 [PMID:21505038]
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
GtoPdb - - 4.7 pIC50 20000 nM IC50
glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
GtoPdb - - 5.1 pIC50 8000 nM IC50
glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
GtoPdb - - 3.7 pIC50 204000 nM IC50
GtoPdb - - 4.3 pIC50 50000 nM IC50

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]