isocarboxazid [Ligand Id: 7204] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1201168 (Enerzer, Isocarboxazid, Isocarboxazida, Isocarboxazide, Marplan, NSC-169893, RO 5-0831, RO-5-0831) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| 8-oxoguanine DNA glycosylase/N-glycosylase/DNA lyase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3396944] [GtoPdb: 3060] [UniProtKB: O15527] | ||||||||
| ChEMBL | Inhibition of human OGG1 incubated for 30 mins using 8-oxo-Gua-containing substrate by TAMRA fluorescence-based assay | B | 4.3 | pIC50 | >50000 | nM | IC50 | US-20170038365-A1. Small molecule inhibitors of 8-oxoguanine dna glycosylase-1 (ogg1) (2017) |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
