isoetarine   Click here for help

GtoPdb Ligand ID: 7205

Synonyms: Bronkometer® | Bronkosol® | WIN-3406
Approved drug Immunopharmacology Ligand
isoetarine is an approved drug (FDA (1979))
Compound class: Synthetic organic
Comment: Isoetharine is a bronchodilator. Note that the US FDA approved drug is isoetharine.
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Click here for structure editor
Physico-chemical Properties
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Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/). All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

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Hydrogen bond acceptors 2
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 72.72
Molecular weight 239.15
XLogP 1.98
No. Lipinski's rules broken 0

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)

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Canonical SMILES CCC(C(c1ccc(c(c1)O)O)O)NC(C)C
Isomeric SMILES CCC(C(c1ccc(c(c1)O)O)O)NC(C)C
InChI InChI=1S/C13H21NO3/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9/h5-8,10,13-17H,4H2,1-3H3
InChI Key HUYWAWARQUIQLE-UHFFFAOYSA-N

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1979))
IUPAC Name Click here for help
4-{1-hydroxy-2-[(propan-2-yl)amino]butyl}benzene-1,2-diol
International Nonproprietary Names Click here for help
INN number INN
1384 isoetarine
Synonyms Click here for help
Bronkometer® | Bronkosol® | WIN-3406
Database Links Click here for help
CAS Registry No. 530-08-5
ChEMBL Ligand CHEMBL1201213
DrugBank Ligand DB00221
DrugCentral Ligand 1491
GtoPdb PubChem SID 178103780
PubChem CID 3762
Search Google for chemical match using the InChIKey HUYWAWARQUIQLE-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HUYWAWARQUIQLE
Search PubMed clinical trials isoetarine
Search PubMed titles isoetarine
Search PubMed titles/abstracts isoetarine
UniChem Compound Search for chemical match using the InChIKey HUYWAWARQUIQLE-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey HUYWAWARQUIQLE-UHFFFAOYSA-N
Wikipedia Isoetarine