INSL5 [Ligand Id: 2000] activity data from GtoPdb

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  • RXFP3 in Human [GtoPdb: 353] [UniProtKB: Q9NSD7]
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  • RXFP4 in Human [GtoPdb: 354] [UniProtKB: Q8TDU9]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
RXFP3 in Human [GtoPdb: 353] [UniProtKB: Q9NSD7]
GtoPdb - - 7.01 pKi - - Ki Eur J Pharmacol (2008) 590: 43-52 [PMID:18582868]
RXFP4 in Human [GtoPdb: 354] [UniProtKB: Q8TDU9]
GtoPdb - - 8.8 pKi - - - J Biol Chem (2005) 280: 292-300 [PMID:15525639];
J Med Chem (2012) 55: 1671-81 [PMID:22257012];
Eur J Pharmacol (2008) 590: 43-52 [PMID:18582868];
J Med Chem (2013) 56: 9509-16 [PMID:24188028];
J Med Chem (2016) 59: 2118-25 [PMID:26824523];
Sci Rep (2019) 9: 17828 [PMID:31780677];
Amino Acids (2016) 48: 987-992 [PMID:26661035]
GtoPdb - - 9.8 pIC50 - - - J Mol Endocrinol (2018) 60: 213-224 [PMID:29535183];
J Med Chem (2013) 56: 9509-16 [PMID:24188028];
J Biol Chem (2005) 280: 292-300 [PMID:15525639];
Amino Acids (2016) 48: 987-992 [PMID:26661035];
J Med Chem (2016) 59: 2118-25 [PMID:26824523];
Sci Rep (2019) 9: 17828 [PMID:31780677];
J Med Chem (2012) 55: 1671-81 [PMID:22257012];
Arch Biochem Biophys (2014) 558: 127-32 [PMID:25043977]
GtoPdb - - 7.7 pEC50 - - - Br J Pharmacol (2017) 174: 1077-1089 [PMID:27243554]
GtoPdb - - 8.94 pEC50 - - - J Biol Chem (2005) 280: 292-300 [PMID:15525639];
Dalton Trans (2008) : 4288-95 [PMID:18682868];
J Mol Endocrinol (2018) 60: 213-224 [PMID:29535183]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.