PSN632408 [Ligand Id: 3319] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1081913 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| GPR119/Glucose-dependent insulinotropic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5652] [GtoPdb: 126] [UniProtKB: Q8TDV5] | ||||||||
| ChEMBL | Agonist activity at GPR119 (unknown origin) by Fluo-4 AM dye based calcium mobilization assay | F | 5.29 | pEC50 | 5130 | nM | EC50 | ACS Med Chem Lett (2016) 7: 579-583 [PMID:27326330] |
| GtoPdb | - | - | 5.3 | pEC50 | - | - | - | Cell Metab (2006) 3: 167-75 [PMID:16517404] |
| ChEMBL | Agonist activity at human GPR119 receptor expressed in HEK293 cells after 30 mins by cAMP assay | F | 5.72 | pEC50 | 1900 | nM | EC50 | J Med Chem (2016) 59: 3579-3592 [PMID:26512410] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
