baricitinib

Ligand id: 7792

Name: baricitinib

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	7
Hydrogen bond donors	1
Rotatable bonds	5
Topological polar surface area	128.94
Molecular weight	371.12
XLogP	0.41
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

IUPAC Name
2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile

IUPAC Name

2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile

International Nonproprietary Names
INN number	INN
9570	baricitinib

Synonyms
INCB-028050 \| INCB028050 \| LY-3009104 \| LY3009104 \| Olumiant®

Synonyms

INCB-028050 | INCB028050 | LY-3009104 | LY3009104 | Olumiant®

Comments
Baricitinib is a JAK1 and 2 selective inhibitor. The compound is orally bioavailable.

Comments

Baricitinib is a JAK1 and 2 selective inhibitor. The compound is orally bioavailable.

Database Links
CAS Registry No.	1187594-09-7
ChEMBL Ligand	CHEMBL2105759
GtoPdb PubChem SID	223366123
PubChem CID	44205240
RCSB PDB Ligand	3JW
Search Google for chemical match using the InChIKey	XUZMWHLSFXCVMG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	XUZMWHLSFXCVMG
Search PubMed clinical trials	baricitinib
Search PubMed titles	baricitinib
Search PubMed titles/abstracts	baricitinib
Search UniChem for chemical match using the InChIKey	XUZMWHLSFXCVMG-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	XUZMWHLSFXCVMG
Wikipedia	Baricitinib