triflupromazine   Click here for help

GtoPdb Ligand ID: 4330

Synonyms: triflupromazine hydrochloride | Vesprin®
Approved drug
triflupromazine is an approved drug (FDA (1957))
Compound class: Synthetic organic
Comment: Triflupromazine is a phenothiazine class antipsychotic drug.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 31.78
Molecular weight 352.12
XLogP 5.23
No. Lipinski's rules broken 1
SMILES / InChI / InChIKey
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Canonical SMILES CN(CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F)C
Isomeric SMILES CN(CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F)C
InChI InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3
InChI Key XSCGXQMFQXDFCW-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1957))
IUPAC Name Click here for help
dimethyl({3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl})amine
International Nonproprietary Names Click here for help
INN number INN
725 triflupromazine
Synonyms Click here for help
triflupromazine hydrochloride | Vesprin®
Database Links Click here for help
CAS Registry No. 146-54-3 (source: Scifinder)
ChEMBL Ligand CHEMBL570
DrugBank Ligand DB00508
DrugCentral Ligand 2742
GtoPdb PubChem SID 178101147
PubChem CID 5568
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Wikipedia Triflupromazine