triflupromazine   Click here for help

GtoPdb Ligand ID: 4330

Synonyms: triflupromazine hydrochloride | Vesprin®
Approved drug
triflupromazine is an approved drug (FDA (1957))
Compound class: Synthetic organic
Comment: Triflupromazine is a phenothiazine class antipsychotic drug.
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 31.78
Molecular weight 352.12
XLogP 5.23
No. Lipinski's rules broken 1
Click here for help
Canonical SMILES CN(CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F)C
Isomeric SMILES CN(CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F)C
InChI InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1957))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
725 triflupromazine
Synonyms Click here for help
triflupromazine hydrochloride | Vesprin®
Database Links Click here for help
CAS Registry No. 146-54-3 (source: Scifinder)
DrugBank Ligand DB00508
DrugCentral Ligand 2742
GtoPdb PubChem SID 178101147
PubChem CID 5568
Search Google for chemical match using the InChIKey XSCGXQMFQXDFCW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XSCGXQMFQXDFCW
Search PubMed clinical trials triflupromazine
Search PubMed titles triflupromazine
Search PubMed titles/abstracts triflupromazine
UniChem Compound Search for chemical match using the InChIKey XSCGXQMFQXDFCW-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey XSCGXQMFQXDFCW-UHFFFAOYSA-N
Wikipedia Triflupromazine