OMO-1

Ligand id: 10507

Name: OMO-1

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 68.86
Molecular weight 374.11
XLogP 5.34
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
6-[difluoro-(6-pyridin-4-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]quinoline
Synonyms
example 60 [WO2007075567A1] | JNJ-38877618 | JNJ38877618 | OMO1
Comments
OMO-1 (formerly JNJ-38877618) is a potent, highly selective and orally bioavailable MET kinase inhibitor. It is being investigated as an anti-tumour agent in advanced solid malignancies. The chemical structure of OMO-1 is one of those claimed in Janssen patent WO2007075567A1 [1].
Database Links
CAS Registry No. 943540-74-7 (source: PubChem)
GtoPdb PubChem SID 387065589
PubChem CID 57654476
Search Google for chemical match using the InChIKey KOAWAWHSMVKCON-UHFFFAOYSA-N
Search Google for chemicals with the same backbone KOAWAWHSMVKCON
Search UniChem for chemical match using the InChIKey KOAWAWHSMVKCON-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone KOAWAWHSMVKCON