ChEMBL ligand: CHEMBL1169 (4-aminosalicylic acid, Aminosalicylate, Aminosalicylic acid, Aminosalicylic Acid, Aminosalicylic acid resin complex, Benzoic acid, 4-amino-2-hydroxy-, Granupas, Granupas (previously para-aminosalicylic acid lucane), NSC-2083, P-aminosalicylic acid, Para-aminosalicylic acid, Parasal, Pas, Paser, Paskalium, Rezipas, Teebacin)
protein tyrosine phosphatase non-receptor type 1/Protein-tyrosine phosphatase 1B in Human [ChEMBL: CHEMBL335] [GtoPdb: 2976] [UniProtKB: P18031] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
protein tyrosine phosphatase non-receptor type 1/Protein-tyrosine phosphatase 1B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL335] [GtoPdb: 2976] [UniProtKB: P18031]
ChEMBL	Dissociation constant for Protein-tyrosine phosphatase 1B	B	2.92	pKd	1200000	nM	Kd	J Med Chem (2004) 47: 3463-3482 [PMID:15214773]
ChEMBL	Dissociation constant against protein tyrosine phosphatase PTB1B receptor was determined	B	2.92	pKd	1200000	nM	Kd	J Med Chem (2003) 46: 4232-4235 [PMID:13678400]
ChEMBL	Binding affinity to N-terminal GST-fused human PTP1B (1 to 288 residues) expressed in Escherichia coli BL21(DE3) by HSQC NMR analysis	B	2.92	pKd	1200000	nM	Kd	J Med Chem (2020) 63: 11420-11435 [PMID:32539387]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]