Synonyms: Holoxan® | Ifex® | MJF-9325 | Z-4942
ifosfamide is an approved drug (FDA (1988))
Compound class:
Synthetic organic
Comment: Ifosfamide is a DNA alkylating drug, and has additional immunosuppressant action. Ifosfamide is biologically inactive. In vivo metabolism is necessary to generate the active substance, isophosphamide mustard (IPM; PubChem CID 100427) [1].
View more information in the IUPHAR Pharmacology Education Project: ifosfamide |
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1988)) |
WHO Essential Medicine | WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version. Click to view more information about the WHO Model Lists of Essential Medicines. |
IUPAC Name |
3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2λ5-oxazaphosphinan-2-one |
International Nonproprietary Names | |
INN number | INN |
2865 | ifosfamide |
Synonyms |
Holoxan® | Ifex® | MJF-9325 | Z-4942 |
Database Links | |
CAS Registry No. | 3778-73-2 |
ChEMBL Ligand | CHEMBL1024 |
DrugBank Ligand | DB01181 |
DrugCentral Ligand | 1421 |
GtoPdb PubChem SID | 178103776 |
PubChem CID | 3690 |
Search Google for chemical match using the InChIKey | HOMGKSMUEGBAAB-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | HOMGKSMUEGBAAB |
Search PubMed clinical trials | ifosfamide |
Search PubMed titles | ifosfamide |
Search PubMed titles/abstracts | ifosfamide |
UniChem Compound Search for chemical match using the InChIKey | HOMGKSMUEGBAAB-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | HOMGKSMUEGBAAB-UHFFFAOYSA-N |
Wikipedia | Ifosfamide |