icatibant   Click here for help

GtoPdb Ligand ID: 667

Synonyms: D-Arg-[Hyp3,Thi5,D-Tic7,Oic8]BK | Firazyr® | HOE 140 | HOE140
Approved drug Immunopharmacology Ligand
icatibant is an approved drug (EMA (2008), FDA (2011))
Comment: Synthetic analogue of bradykinin. There is some ambiguity in the literature and on online resources as to the exact chemical structure and stereochemistry of icatibant. Therefore, we have chosen not to include a chemical structure here. Users should note that there may not be agreement in the structures represented in the external links provided above.
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Classification Click here for help
Compound class Peptide or derivative
Approved drug? Yes (EMA (2008), FDA (2011))
International Nonproprietary Names Click here for help
INN number INN
6922 icatibant
Synonyms Click here for help
D-Arg-[Hyp3,Thi5,D-Tic7,Oic8]BK | Firazyr® | HOE 140 | HOE140
Database Links Click here for help
BindingDB Ligand 50142947
CAS Registry No. 130308-48-4 (source: Scifinder)
ChEMBL Ligand CHEMBL2028850
DrugBank Ligand DB06196
GtoPdb PubChem SID 135652196
PubChem CID 71364
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Wikipedia Icatibant