norfloxacin   Click here for help

GtoPdb Ligand ID: 12408

Synonyms: AM-715 | Chibroxin® | MK-0366 | Noroxin®
Approved drug
norfloxacin is an approved drug (FDA (1986), EMA)
Compound class: Synthetic organic
Comment: Norfloxacin is a fluoroquinolone compound with broad-spectrum antibacterial activity [3].
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 72.88
Molecular weight 319.33
XLogP 1.69
No. Lipinski's rules broken 0
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Canonical SMILES CCN1C=C(C(=O)C2=C1C=C(C(=C2)F)N3CCNCC3)C(=O)O
Isomeric SMILES CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O
InChI InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1986), EMA)
IUPAC Name Click here for help
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
International Nonproprietary Names Click here for help
INN number INN
5105 norfloxacin
Synonyms Click here for help
AM-715 | Chibroxin® | MK-0366 | Noroxin®
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Norfloxacin
Other databases
CAS Registry No. 70458-96-7 (source: Scifinder)
ChEBI CHEBI:100246
DrugBank Ligand DB01059
DrugCentral Ligand 1967
GtoPdb PubChem SID 479821199
PubChem CID 4539
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UniChem Compound Search for chemical match using the InChIKey OGJPXUAPXNRGGI-UHFFFAOYSA-N
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