lacosamide   Click here for help

GtoPdb Ligand ID: 7472

Synonyms: ADD 234037 | erlosamide | harkeroside | SPM 927 | Vimpat®
Approved drug PDB Ligand
lacosamide is an approved drug (EMA and FDA (2008))
Compound class: Synthetic organic
Comment: Lacosamide is a functionalized amino acid anticonvulsant drug [2].
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 67.43
Molecular weight 250.13
XLogP 0.51
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES COCC(C(=O)NCc1ccccc1)NC(=O)C
Isomeric SMILES COC[C@H](C(=O)NCc1ccccc1)NC(=O)C
InChI InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
InChI Key VPPJLAIAVCUEMN-GFCCVEGCSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (EMA and FDA (2008))
IUPAC Name Click here for help
(2R)-2-acetamido-3-methoxy-N-(phenylmethyl)propanamide
International Nonproprietary Names Click here for help
INN number INN
8094 lacosamide
Synonyms Click here for help
ADD 234037 | erlosamide | harkeroside | SPM 927 | Vimpat®
Database Links Click here for help
CAS Registry No. 175481-36-4
ChEMBL Ligand CHEMBL58323
DrugBank Ligand DB06218
DrugCentral Ligand 4310
GtoPdb PubChem SID 187051775
PubChem CID 219078
RCSB PDB Ligand LQO
Search Google for chemical match using the InChIKey VPPJLAIAVCUEMN-GFCCVEGCSA-N
Search Google for chemicals with the same backbone VPPJLAIAVCUEMN
Search PubMed clinical trials lacosamide
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UniChem Compound Search for chemical match using the InChIKey VPPJLAIAVCUEMN-GFCCVEGCSA-N
UniChem Connectivity Search for chemical match using the InChIKey VPPJLAIAVCUEMN-GFCCVEGCSA-N
Wikipedia Lacosamide