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Molecular properties generated using the CDK
|Compound class||Natural product or derivative|
|Ligand families/groups||Antimalarial ligands|
|Approved drug?||Yes (FDA (2009) in combination with lumefantrine)|
|International Nonproprietary Names|
|β-artemether | beta-artemether|
|Artemether is a semisynthetic derivative of artemisinin, a natural product isolated from the quinghaosu or sweet wormwood plant (Artemisia annua). Synthesis yields two crystalline anomers, α- and β-artemether, the latter predominates and is marginally more active .
Artemether is a prodrug that is converted to the active metabolite artenimol (dihydroartemisinin).
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
|CAS Registry No.||71963-77-4 (source: Scifinder)|
|GtoPdb PubChem SID||374883842|
|RCSB PDB Ligand||D8Z|
|Search Google for chemical match using the InChIKey||SXYIRMFQILZOAM-HVNFFKDJSA-N|
|Search Google for chemicals with the same backbone||SXYIRMFQILZOAM|
|Search PubMed clinical trials||artemether|
|Search PubMed titles||artemether|
|Search PubMed titles/abstracts||artemether|
|Search UniChem for chemical match using the InChIKey||SXYIRMFQILZOAM-HVNFFKDJSA-N|
|Search UniChem for chemicals with the same backbone||SXYIRMFQILZOAM|
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Cat. No. 6818