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ChEMBL ligand: CHEMBL1929396 (Anagliptin, CWP-403, Sk-0403, SK-0403, Suiny) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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fibroblast activation protein alpha/Fibroblast activation protein alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4683] [GtoPdb: 2365] [UniProtKB: Q12884] | ||||||||
ChEMBL | Inhibition of human recombinant FAP expressed in baculovirus-infected Sf9 insect cells using H-Ala-Pro-AFC as substrate after 60 mins by fluorescence assay | B | 4.14 | pIC50 | 72700 | nM | IC50 | Bioorg. Med. Chem. (2011) 19: 7221-7227 [PMID:22019046] |
dipeptidyl peptidase 4 in Human [GtoPdb: 1612] [UniProtKB: P27487] | ||||||||
GtoPdb | Inhibition of human recombinant DPP-4 in vitro | - | 8.42 | pIC50 | 3.8 | nM | IC50 | Bioorg Med Chem (2011) 19: 7221-7 [PMID:22019046] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]