ChEMBL ligand: CHEMBL1162 (Heather, Primolut N, Norlutate, Aygestin, SC-4640, Combipatch, Micronor HRT, Utovlan, NSC-9564, Noriday, Camila, Nor-Qd, Activella, Femhrt, Norlutin, Errin, Menzol, Norethisterone, Incassia, Jencycla, Norethindrone, Norethidrone, Micronor)
Androgen receptor/Androgen Receptor in Rat [ChEMBL: CHEMBL3072] [GtoPdb: 628] [UniProtKB: P15207] This target only has 1 pki data point 1 CHEMBL1162_lig_chart_1 Androgen Receptor Rat There should be some charts here, you may need to enable JavaScript!
Estrogen receptor-α/Estrogen receptor alpha in Human [ChEMBL: CHEMBL206] [GtoPdb: 620] [UniProtKB: P03372] This target only has 1 pki data point 2 CHEMBL1162_lig_chart_2 Estrogen receptor alpha Human There should be some charts here, you may need to enable JavaScript!
Glucocorticoid receptor in Human [ChEMBL: CHEMBL2034] [GtoPdb: 625] [UniProtKB: P04150] This target only has 1 pki data point 3 CHEMBL1162_lig_chart_3 Glucocorticoid receptor Human There should be some charts here, you may need to enable JavaScript!
Progesterone receptor in Human [ChEMBL: CHEMBL208] [GtoPdb: 627] [UniProtKB: P06401] Progesterone receptor in Bovine [ChEMBL: CHEMBL1909044] [UniProtKB: Q690N0] 4 CHEMBL1162_lig_chart_4 Progesterone receptor HumanBovine There should be some charts here, you may need to enable JavaScript!
SERT/Serotonin transporter in Human [ChEMBL: CHEMBL228] [GtoPdb: 928] [UniProtKB: P31645] This target only has 1 pki data point 5 CHEMBL1162_lig_chart_5 Serotonin transporter Human There should be some charts here, you may need to enable JavaScript!
Testis-specific androgen-binding protein in Human [ChEMBL: CHEMBL3305] [UniProtKB: P04278] This target only has 0 pki data point 6 CHEMBL1162_lig_chart_6 Testis-specific androgen-binding protein Human There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Androgen receptor/Androgen Receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3072] [GtoPdb: 628] [UniProtKB: P15207]
ChEMBL	DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone)	B	7.82	pKi	15	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)	B	6.92	pIC50	120.23	nM	IC50	J. Med. Chem. (2005) 48: 5666-5674 [PMID:16134935]
ChEMBL	DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone)	B	7.66	pIC50	22	nM	IC50	DrugMatrix in vitro pharmacology data
Estrogen receptor-α/Estrogen receptor alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL206] [GtoPdb: 620] [UniProtKB: P03372]
ChEMBL	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	B	6.64	pKi	231	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol)	B	6.09	pIC50	808	nM	IC50	DrugMatrix in vitro pharmacology data
Glucocorticoid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2034] [GtoPdb: 625] [UniProtKB: P04150]
ChEMBL	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	B	6.71	pKi	197	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	B	6.36	pIC50	433	nM	IC50	DrugMatrix in vitro pharmacology data
Progesterone receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL208] [GtoPdb: 627] [UniProtKB: P06401]
ChEMBL	Dissociation constant for progesterone receptor	B	9.4	pKd	0.4	nM	Kd	J. Med. Chem. (2004) 47: 3381-3387 [PMID:15189034]
ChEMBL	The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.	B	8.73	pKi	1.87	nM	Ki	J. Med. Chem. (1998) 41: 303-310 [PMID:9464361]
ChEMBL	Binding affinity against Progesterone receptor in human TE85 osteosarcoma cells was determined using (Z)-[125I]-17-alpha-(2-iodovinyl)-19-nor-testosterone as radioligand	B	8.49	pIC50	3.2	nM	IC50	J. Med. Chem. (1995) 38: 4880-4884 [PMID:8523400]
ChEMBL	Agonistic activity was measured for modulation of hPR-B (human progesterone receptor) in co-transfected CV-1 cells.	F	8.66	pEC50	2.2	nM	EC50	J. Med. Chem. (1998) 41: 303-310 [PMID:9464361]
GtoPdb	-	-	8.66	pEC50	2.2	nM	EC50	J. Med. Chem. (1998) 41: 303-10 [PMID:9464361]
Progesterone receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1909044] [UniProtKB: Q690N0]
ChEMBL	DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020)	B	8.91	pKi	1.22	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020)	B	8.03	pIC50	9.34	nM	IC50	DrugMatrix in vitro pharmacology data
SERT/Serotonin transporter in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL228] [GtoPdb: 928] [UniProtKB: P31645]
ChEMBL	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	B	5.62	pKi	2411	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine)	B	5.34	pIC50	4537	nM	IC50	DrugMatrix in vitro pharmacology data
Testis-specific androgen-binding protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3305] [UniProtKB: P04278]
ChEMBL	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	B	7.97	pKd	10.72	nM	Kd	J. Med. Chem. (2008) 51: 2047-2056 [PMID:18330978]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]