isoflurane [Ligand Id: 2505] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1256 (Aerrane, COMPOUND 469, COMPOUND-469, Forane, Isoflurane)
  • TRPA1 in Rat [GtoPdb: 485] [UniProtKB: Q6RI86]
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  • K2P3.1 in Rat [GtoPdb: 515] [UniProtKB: O54912]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TRPA1 in Rat [GtoPdb: 485] [UniProtKB: Q6RI86]
GtoPdb Patch clamp - 3.7 pEC50 - - - Proc Natl Acad Sci USA (2008) 105: 8784-9 [PMID:18574153]
K2P3.1 in Rat [GtoPdb: 515] [UniProtKB: O54912]
GtoPdb - - 2.7 pEC50 - - - J Neurosci (2002) 22: 1256-65 [PMID:11850453]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]