cefpodoxime   Click here for help

GtoPdb Ligand ID: 10780

Synonyms: RU-51746 | Vantin®
Approved drug
cefpodoxime is an approved drug (FDA (1992))
Compound class: Synthetic organic
Comment: Cefpodoxime (proxetil) is a broad-spectrum, oral, third generation cephalosporin antibacterial that is active against most Gram-positive and Gram-negative bacteria [1].
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 209.98
Molecular weight 427.06
XLogP -2.93
No. Lipinski's rules broken 0
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Canonical SMILES CO/N=C(/c1csc(n1)N)\C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)COC
Isomeric SMILES CO/N=C(/c1csc(n1)N)\C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)COC
InChI InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1992))
IUPAC Name Click here for help
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
International Nonproprietary Names Click here for help
INN number INN
6123 cefpodoxime
Synonyms Click here for help
RU-51746 | Vantin®
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Cefpodoxime
Other databases
CAS Registry No. 80210-62-4 (source: PubChem)
ChEMBL Ligand CHEMBL1672
GtoPdb PubChem SID 405560221
PubChem CID 6335986
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