TUG-1375

Ligand id: 10107

Name: TUG-1375

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 108.94
Molecular weight 442.08
XLogP 4.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2R,4R)-2-(2-chlorophenyl)-3-(4-(3,5-dimethylisoxazol-4-yl)benzoyl)thiazolidine-4-carboxylic acid
Synonyms
compound 31 [PMID: 30247908] | TUG1375
Comments
TUG-1375 was designed as a selective free fatty acid receptor 2 (FFA2/GPR43) agonist, as a pharmacological tool that is suitable for the study of FFA2 receptor function in vitro and in vivo [1]. FFA2 is known to be involved in regulation of metabolism, appetite, fat accumulation and inflammatory responses.
Database Links
GtoPdb PubChem SID 381118817
Search Google for chemical match using the InChIKey RZAMDGBOOPJHJQ-NQIIRXRSSA-N
Search Google for chemicals with the same backbone RZAMDGBOOPJHJQ
Search UniChem for chemical match using the InChIKey RZAMDGBOOPJHJQ-NQIIRXRSSA-N
Search UniChem for chemicals with the same backbone RZAMDGBOOPJHJQ