ingenol mebutate   Click here for help

GtoPdb Ligand ID: 7443

Synonyms: PEP-005 | Picato®
Approved drug
ingenol mebutate is an approved drug (FDA & EMA (2012))
Comment: Ingenol mebutate is extracted from the plant Euphorbia peplus.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 104.06
Molecular weight 430.24
XLogP 3.21
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CC=C(C(=O)OC1C(=CC23C1(O)C(O)C(=CC(C3=O)C1C(CC2C)C1(C)C)CO)C)C
Isomeric SMILES C/C=C(\C(=O)O[C@H]1C(=C[C@]23[C@]1(O)[C@H](O)C(=C[C@H](C3=O)[C@H]1[C@@H](C[C@H]2C)C1(C)C)CO)C)/C
InChI InChI=1S/C25H34O6/c1-7-12(2)22(29)31-21-13(3)10-24-14(4)8-17-18(23(17,5)6)16(20(24)28)9-15(11-26)19(27)25(21,24)30/h7,9-10,14,16-19,21,26-27,30H,8,11H2,1-6H3/b12-7-/t14-,16+,17-,18+,19-,21+,24+,25+/m1/s1
InChI Key VDJHFHXMUKFKET-WDUFCVPESA-N
Classification Click here for help
Compound class Natural product or derivative
Approved drug? Yes (FDA & EMA (2012))
International Nonproprietary Names Click here for help
INN number INN
9006 ingenol mebutate
Synonyms Click here for help
PEP-005 | Picato®
Database Links Click here for help
CAS Registry No. 75567-37-2
ChEBI CHEBI:66913
ChEMBL Ligand CHEMBL1863513
DrugBank Ligand DB05013
DrugCentral Ligand 4226
GtoPdb PubChem SID 178104015
PubChem CID 6918670
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Wikipedia Ingenol mebutate

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Tocris
PEP 005
Cat. No. 4054