Top ▲

The IUPHAR/BPS Guide to PHARMACOLOGY complete ligand list

Click here for help
Non-peptidic, biogenic compounds derived from living organisms and their close synthetic derivatives.
Download as CSV

A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   V   W   X   Y   Z  

Ligand name ID Synonyms
A Back to top
abscisic acid Immunopharmacology Ligand 10362 (+/-)-(cis,trans)-abscisic acid, (+/-)-Abscisic acid, (RS)-Abscisic acid, ABA
absinthin 12458 (+)-absinthin, absynthin
aconitine 2617
agatoxin 489 2484 AG 489
ajmalicine Approved drug PDB Ligand 8746 delta-yohimbine, raubasine, rauvasan, rauwolfia alkaloid
alchivemycin A 13437
alcuronium 341
allicin 2419
aloin 12498 aloin A/B
Altromycin B 10964
amarogentin 12459
amphomycin 13516 glumamycin
anacardic acid 6999
apicidin Antimalarial Ligand 7495 OSI-2040
apigenin PDB Ligand 4136
aplithianine A PDB Ligand 13089 compound 1 [PMID: 37843072]
apramycin PDB Ligand 10760 EBL-1003, EL-857, EL857, nebramycin factor 2, nebramycin II
arctigenin PDB Ligand 13586 (-)-Arctigenin
arecoline 296 methylarecaiden, methylarecaidin, taeniolin
argiotoxin PDB Ligand 4138 argiotoxin 636
Aristoteline 13176
artemisinin Antimalarial Ligand 9954 qinghaosu
artenimol Approved drug Antimalarial Ligand 9957 DHA, dihydroartemisinin, GNF-Pf-5634
artepillin C 6302
α-asarone 13278 (α)-asarone, trans-asarone
(R)-asimilobine 13235 (-)-asimilobine, R-(-)-asimilobine
atropine Approved drug 320 Atropen®, hyoscyamine
 
B Back to top
bacitracin A Approved drug 12812
bacoside A3 13094
baicalein PDB Ligand 5144 5,6,7-trihydroxyflavone
baicalin PDB Ligand Immunopharmacology Ligand 13076 7-D-glucuronic acid-5,6-dihydroxy-flavone, Baicalein 7-glucuronide, compound 15 [PMID: 37666112]
balanol PDB Ligand 8142 azepinostatin
batrachotoxin 2619
bekanamycin Approved drug PDB Ligand 12182 kanamycin B, nebramycin V
bengalensol 12469
benzoate 4565 benzoic acid
benzosceptrin C 13127 compound 6 [PMID: 20166736]
berberine PDB Ligand 11353 umbellatine
bergapten 12431 5-Methoxypsoralen, 5-MOP, bergaptene, Heraclin, O-Methylbergaptol
beta-gentiobiose 12452 6-O-beta-D-glucopyranosyl-D-glucopyranose
betulinic acid PDB Ligand 3945
bicuculline PDB Ligand 2312 bicuculline methiodide
bilobalide 2366
BIO101 PDB Ligand 11987 20-Hydroxyecdysone, beta-Ecdysone, Crustecdysone, Ecdysterone, Sarconeos
biochanin A PDB Ligand 2829 4'-methylgenistein
Bis1 9572 Tz‐BBA
bisandrographolide 2502
bongkrek acid PDB Ligand 4689 BKA, bongkrekic acid, flavotoxin A
borneol 6413 (+)-borneol, isoborneol
boromycin Antimalarial Ligand 13447
borrelidin Antimalarial Ligand 11306 (-)-borrelidin
brucine 342 10,11-dimethoxy strychnine
 
C Back to top
caffeic acid PDB Ligand 5155
caffeine Approved drug PDB Ligand 407 Peyona®
calphostin C 5156
calyculin A 13083 (-)-calyculin A, hemicalyculin A
camphor 2422 2-bornanone, 2-camphanone, bornan-2-one
cannabichromene 11093 (+/-)-Cannabichromene, cannabichrome, CBC
cannabidiol Approved drug PDB Ligand 4150 CBD, Epidiolex®, GWP42003-P, nabiximols (CBD + THC, fixed-dose oral spray), Sativex® (CBD + THC, fixed-dose oral spray)
cannabidivarin 11092 CBDV, GWP42006
cannabigerol 11094 CBG
cannabigeroquinone 13406 CBGQ, phytocannabinoid 14 [PMID: 38408345], VCE-003
cantharidin Approved drug 13081 Ycanth® (0.7% solution, single-use topical applicator)
caprazamycin B 13474
capreomycin IB Approved drug 13256 Capastat®
capsaicin Approved drug PDB Ligand 2486 Qutenza®
capuramycin PDB Ligand 13471 A-500359 B, antibiotic 446-S3-1
carboxyatractyloside PDB Ligand 4572 CATR
carvacrol PDB Ligand 2497
carveol 6417 L-carveol
catechin PDB Ligand 13091 (+)-catechin, catechol, cianidanol, D-Catechin
cationomycin 11002 BRN-6263205, BRN6263205, LS-52659, LS52659
celastrol PDB Ligand Immunopharmacology Ligand 10386 compound 2 [PMID: 28621943]
cephalosporin P1 12330 acremonic acid
cervimycin C 13603
chaetocin 8388
chalcomycin 11058
chelerythrine PDB Ligand 5953 broussonpapyrine, cheleritrine, chelerythrine hydroxide, toddalin
chlorocardicin 11044
chlorogenic acid 12477 3-O-caffeoylquinic acid, caffeoyl quinic acid, chlorogenate
chlorotonil A Antimalarial Ligand 13589
chlortetracycline Approved drug PDB Ligand 13537 Aureomycin®
chrysin PDB Ligand 8789 NSC-407436
cimifugin 12555 Cimitin
cinchonine 13363 (+)-Cinchonine, D-Cinchonine
cinnamtannin B1 PDB Ligand 13186 Cinnamtannin B-1, CTB-1
citibrasine 8561 compound 7 [PMID: 21277783]
citral PDB Ligand 6327 citral a, geranial, geranialdehyde, trans-citral
Citrusinine II 11377 Citrusinine-II, compound 5 [PMID: 21277783]
CJ-15,801 Antimalarial Ligand 10610 CJ-15801
cladosporin PDB Ligand Antimalarial Ligand 10247 asperentin
clavulanic acid Approved drug PDB Ligand 11128 BRL-14151, BRL-14151K, BRL14151, clavulanate, MM 14151
7α-Cl-ginkgolide B 1840 7α-Cl-GB
clorobiocin PDB Ligand 12127 chlorobiocin, RP 18,631
clovibactin 13080 Novo29
cocaine Approved drug PDB Ligand 2286
codeine Approved drug 1673 Codicept®, methylmorphine
cohumulone 12422 (+/-)-cohumulone
colistin Approved drug 10794 Colobreathe®, polymyxin E, Promixin®
compound 11 [PMID: 30694059] 13327 compound 1 [PMID: 23180340]
compound 4 [PMID: 39046805] 13528
compound 5 [PMID: 10869194] 8843
conessine 8981
Corallopyronin A 11029 CorA, LS-54950, LS54950
cordycepin PDB Ligand 4630 3'-deoxyadenosine
correolide 2555
cortistatin A PDB Ligand 9885 (+)-cortistatin A, 17-epi-cortistatin A
corynanthine 5345 rauhimbine
coumestrol PDB Ligand 12437
crofelemer Approved drug 7453 Fulyzaq®, SP-303
cucurbitacin B 12432 (+)-Cucurbitacin B, Amarine, Datisca principle B
curcumin PDB Ligand 7000
cyclopamine PDB Ligand 10328 11-Deoxyjervine
cyclopiazonic acid 5350 α-cyclopiazonic acid, NSC 117181
cyclothialidine 10988 Ro 09-1437
cytisine PDB Ligand 5347 baptitoxine, cytisin, cytisinicline, sophorine
cytochalasin B PDB Ligand 5334 phomin
 
D Back to top
dactimicin 11001 Formimidoyl-fortimicin A, SF-2052, SF2052
daidzein PDB Ligand 2828 7,4'-dihydroxyisoflavone
D-(-)-Amygdalin 12451 amygdaloside, D-amygdalin, glucoprunasin, isoamygdalin
datiscetin PDB Ligand 12440
daunorubicin Approved drug PDB Ligand 7063 Cerubidine®, daunomycin, FI-6339, NDC-0082-4155, RP-13057
declovanillobiocin 12128 novclobiocin 313
defibrotide Approved drug 9087 Defitelio®
14-Deoxy-11,12-didehydroandrographolide Immunopharmacology Ligand 13464 ddA (14-deoxy-11,12-didehydroandrographolide)
1-deoxynojirimycin PDB Ligand 4642 AT-2220, duvoglustat, S-GI
deserpidine Approved drug 7064 Harmonyl®, recanescin
1,9-dideoxyforskolin 4100
difficidin 11062
digoxin Approved drug PDB Ligand 4726 Lanoxin®
dihydroergocristine 278
domoic acid PDB Ligand 4181 domoate, NSC 288031
doxorubicin Approved drug PDB Ligand 7069 Adriamycin®, Caelyx® (liposomal doxorubicin), Doxil®, doxorubicin hydrochloride
D-phenyllactic acid PDB Ligand 12418 (-)-3-Phenyllactic acid, (S)-phenyllactic acid, D-PLA
dysiherbaine PDB Ligand 4185
 
E Back to top
(E)-beta-caryophyllene 13282 (-)-(E)-Caryophyllene, (-)-trans-Caryophyllene, (E)-β-caryophyllene (BCP)
ellagic acid PDB Ligand 13035 benzoaric acid, eleagic acid
Embelin PDB Ligand 11209
emetine PDB Ligand 11087
enviomycin Approved drug 13276 Tuberactin®, tuberactinomycin N
epibatidine 5348 (+)-epibatidine, CMI 488
(-)-Epicatechin PDB Ligand 12497 (2R,3R)-(-)-Epicatechin, epi-Catechin, epi-Catechol, L-Epicatechin
epicatechin gallate 12462 (-)-Epicatechin gallate, (-)-Epicatechin-3-O-gallate, epicatechin monogallate, L-Epicatechin gallate
epigallocatechin PDB Ligand 12461 (-)-EGC, (-)-Epigallocatechin
epigallocatechin-3-gallate PDB Ligand 7002 EGCG, EGCG, epigallocatechin gallate
7-epi-ginkgolide C 1848 7-epi-GC
(±)-Equol 12441 (+/-)-Equol, (R,S)-Equol
eremomycin 10959 A82846A
α-ergocryptine 271
(+/-)-Eriodictyol 12442
eriodictyol chalcone 12443 2',3,4,4',6'-Pentahydroxychalcone, Eriodictyolchalcone
erythromycin Approved drug PDB Ligand 1456 EM-A, E-Mycin®, Erythrocin®, erythromycin-A
esculetin PDB Ligand 5180 6,7-dihydroxycoumarin, aesculetin, cichorigenin
eucalyptol 2464
eugenol PDB Ligand 2425
evybactin 12922 GLXC-26146
 
F Back to top
farnesol 3215 FCI 119a
fascaplysin 5969
feldamycin 10979 BMY-28565, BMY28565, U-48266
Ferrimycin A1 10966
7α-F-ginkgolide B 1841 7α-F-GB
ficellomycin 10965 U-47,929, U-47929, U47929
fisetin PDB Ligand 5182
flagellin 4931
flavone PDB Ligand 409
formate 4540 formic acid, HCOO-
forskolin PDB Ligand 5190 coleonol
forsythoside B Immunopharmacology Ligand 10303
fosmidomycin PDB Ligand Antimalarial Ligand 9739 FR-31564
FR-49175 3150 AC1L4YI4, bis(methylthio)gliotoxin, dimethylgliotoxin, FR 49175
 
G Back to top
galangin PDB Ligand 410 3,5,7-trihydroxyflavone, 3,5,7-triOH-flavone, norizalpinin, NSC-407229
gallic acid PDB Ligand 5549 pyrogallol-5-carboxylic acid
gamma-valerolactone 13648 γ-valerolactone, 4-Valerolactone
garcinoic acid 10734 tocotrienoloic acid, trans-delta-tocotrienoloic acid
garcinol 7001
geldanamycin PDB Ligand 9829
geraniol PDB Ligand 2467
gingerol 2428 6-Gingerol, [6]-Gingerol
ginkgolide A 1861
ginkgolide B 1862 GKB, BN 52021
ginkgolide C 1863 BN 52022
ginkgolide J 1864
ginsenoside Rg3 7658 (20S)-ginsenoside Rg3
gluconate 4519
glycyrrhizin 4688
goitrin 12495 (±)-goitrin, DL-Goitrin
gossypol PDB Ligand 4204
grandinin 12436
grassystatin A 8674
grayanotoxin III 2628
grifolic acid 5588 ilicicolinic acid B
grifolic acid methyl ether 5589
grosheimin 12468 grossheimin
guggulsterone 2745 E-guggulsterone, guggulsterones E, pregna-4,17-diene-3,16-dione
guvacine 4691
 
H Back to top
harmaline 13140
harmine PDB Ligand Immunopharmacology Ligand 9352
hedamycin 10958 antibiotic B 26,158, B26158, NSC-70929
helvolic acid 12329 fumigacin
hematoxylin 13599 (+)-haematoxylin, haematoxylin, hydroxybrasilin, hydroxybrazilin
herbimycin A 5984
hesperetin PDB Ligand 10953 3',5,7-Trihydroxy-4'-methoxyflavanone, NP-13, NSC-57654
himbacine 324
homoeriodictyol 12444 (+/-)-5,7,4'-Trihydroxy-3'-methoxyflavanone, (+/-)-Homoeriodictyol
Honokiol PDB Ligand 11610
HS-142-1 4952 HS142-1
α-humulene PDB Ligand 13236 alpha-caryophyllene, alpha-Humulene, humulene
4-hydroxybenzaldehyde 13597
3β-hydroxydihydrocostunolide 12472
6-Hydroxy-5,7-dimethoxyflavone Immunopharmacology Ligand 9878 UFM-24, UFM24
ω-Hydroxyemodin 11005 Citreorosein, omega-Hydroxyemodin
5-Hydroxymethyl-2-furfural PDB Ligand 10939 5HMF
hygromycin A 13623 homomycin, totomycin
hymeglusin 5886 antibiotic 1233A, F-244, L-659,699
hyperforin 2764
hypericin 11248
hypoglaucin A 842 (-)-hypoglaucine A
 
I Back to top
ibogaine PDB Ligand 13148 (-)-Ibogaine, (5β)-12-methoxyibogamine, 12-Methoxyibogamine
ibotenic acid 1371 ibotenate
icariside II 10686 baohuoside I
idarubicin Approved drug PDB Ligand 7083 Idamycin®, IMI-30, Zavedos®
indanomycin 10949 X-14547A
inecalcitol 7747 TX522
ingenol mebutate Approved drug PDB Ligand 7443 PEP-005, Picato®
ionomycin 13591 SQ-23377
irigenol 11564 compound 4 [PMID: 28621943], UI1956
Isochlorogenic acid A 12548 3,5-DCQA, 3,5-Dicaffeoylquinic acid
Isochlorogenic acid B 12549 3,4-Dicaffeoylquinic acid, 3,4-DICQA
isocorypalmine 13571 (S)-Isocorypalmine, l-Isocorypalmine, tetrahydrocolumbamine
isoquinoline alkaloid 15 [PMID: 33485157] 13568 N,O-dimethylcoclaurine N-oxide
isosakuranetin 10299 4'-Methylnaringenin, naringenin 4'-methyl ether
isovanillobiocin 12129 novclobiocin 312
 
J Back to top
jobosic acid 13405 compound 1 [PMID: 38781491]
joro spider toxin 4229
josamycin Approved drug 12924 kitasamycin A3, leucomycin A3, turimycin A5
juglone 13647
 
K Back to top
K-252a 336 K252a, ST50826373, staurosporine aglycone
kaempferitrin 13277 kaempferol 3,7-dirhamnoside, lespedin, lespenefril
kaempferol PDB Ligand 11052 Robigenin
kainate 4231
kallstroemin D 843
kanamycin Approved drug PDB Ligand 12132 kanamycin A
Katanosin B 10970 Lysobactin
kibdelomycin A 11016
kuwanon H 622 kuwanone H
 
L Back to top
lactivicin 11022 compound 1 [PMID: 17676039], LTV
lactucopicrin 12499 lactopicrin, lactupicrin
L-azetidine-2-carboxylate PDB Ligand 4686
leinamycin 11041 DC-107, DC107
linalool 2469
liposidomycin B 13520
(S)-liquiritigenin PDB Ligand Immunopharmacology Ligand 8899
lobeline PDB Ligand 13498 α-lobeline, (-)-lobeline
loureirin A 13446
lovastatin Approved drug PDB Ligand Immunopharmacology Ligand 2739 (+)-mevinolin, 6α-methylcompactin, Mevacor®
LPS 5019 lipopolysaccharide derived from Gram-negative bacteria
luminamicin 11053 coloradocin, LS-90907
lupulone 12445 beta-Bitter acid, beta-Lupulic acid, Lupolon
lutein 13099 E 161b, xanthophyll
luteolin PDB Ligand Antimalarial Ligand 5215
lysergic acid 139 (+)-lysergic acid, D-lysergic acid, isolysergic acid
lysinomicin 10969
 
M Back to top
malvidin-3-glucoside 12427 Enin, Malvidin 3-O-beta-D-glucoside, Malvidin 3-O-glucoside, Oenin
mangostanin 13468 9-Hydroxycalabaxanthone
α-mangostin PDB Ligand 13469 alpha-mangostin
(-)-menthol Approved drug 2430 l-menthol, levomenthol
mersacidin 11014 M87 1551, M87-1551
mescaline 13139 3,4,5-Trimethoxyphenethylamine, mescalin, mezcalin, Tmpea
meso-DAP PDB Ligand 5021 meso-diaminopimeilic acid
methoxsalen Approved drug PDB Ligand 12457 8-Methoxypsoralen, 8-MOP, xanthotoxin, zanthotoxin
6-methoxysakuranetin 9111 compound 33 [PMID: 21650152]
6-Methylflavone 12466 6-methyl-2-phenylchromen-4-one
methyllycaconitine PDB Ligand 4005
microcystin-LR 4735 toxin-LR
micronomicin Approved drug 12162 gentamicin C2b, Sagamicin®, XK-62-2
midecamycin Approved drug 13158 espinomycin A, platenomycin B1, rubimycin, SF-837, turimycin P3
mithramycin Approved drug PDB Ligand 8394 aureolic acid, Mithracin®, mithramycin A, MMA
mitomycin C Approved drug 7089 Mitosol®, NSC-26980
mitragynine 13149 (-)-Mitragynine
moracin M 13466
morin PDB Ligand 411 aurantica, calico yellow, toxylon pomiferum
morphine Approved drug PDB Ligand 1627 morphine sulfate, Ms Contin®, Oramorph®
muraminomicin F 13519
muramyl dipeptide PDB Ligand 5024 MDP
muraymycin D2 PDB Ligand 13501