Synonyms: BRL-14151 | BRL-14151K | BRL14151 | clavulanate
clavulanic acid is an approved drug
Compound class:
Synthetic organic
Comment: Clavulanic acid is a β-lactamase inhibitor that was isolated from Streptomyces clavuligerusi. It is used in combination with β-lactam antibiotics and does not have inherent antibiotic activity. Clavulanic acid can overcome antibiotic resistance in bacteria that secrete β-lactamase. In the WHO Essential Medicines list as the mixture of amoxicillin + clavulanic acid (co-amoxiclav).
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes |
WHO Essential Medicine | WHO Model List of Essential Medicines (21st List, 2019). Access PDF version. |
IUPAC Name ![]() |
(2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
International Nonproprietary Names ![]() |
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INN number | INN |
4948 | clavulanic acid |
Synonyms ![]() |
BRL-14151 | BRL-14151K | BRL14151 | clavulanate |
Database Links ![]() |
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CAS Registry No. | 58001-44-8 (source: PubChem) |
ChEBI | CHEBI:48947 |
ChEMBL Ligand | CHEMBL777 |
GtoPdb PubChem SID | 434122188 |
PubChem CID | 5280980 |
RCSB PDB Ligand | J01 |
Search Google for chemical match using the InChIKey | HZZVJAQRINQKSD-PBFISZAISA-N |
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Search UniChem for chemical match using the InChIKey | HZZVJAQRINQKSD-PBFISZAISA-N |
Search UniChem for chemicals with the same backbone | HZZVJAQRINQKSD |