ChEMBL ligand: CHEMBL445740 (Beta-Caryophylene, .beta.-caryophyllene, Beta-caryophyllene, Caryophyllene, (-)-(e)-caryophyllene, FEMA NO. 2252, NSC-11906, Trans-.beta.-caryophyllene, (-)-trans-caryophyllene, Trans-caryophyllene)
CB2 receptor/Cannabinoid CB2 receptor in Human [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
CB2 receptor/Cannabinoid CB2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
ChEMBL	Displacement of [3H]CP55940 from human CB2 expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting method	B	6.82	pKi	150	nM	Ki	Eur J Med Chem (2018) 157: 198-228 [PMID:30096653]
GtoPdb	Agonist potency at recombinant human CB2 receptor expressed in CHOK1 cells; determined as inhibition of forskolin-stimulated cAMP formation.	-	5.72	pEC50	1900	nM	EC50	Eur J Med Chem (2018) 157: 198-228 [PMID:30096653]
ChEMBL	Agonist activity at recombinant human Cb2 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP levels measured up to 30 mins by luminescence assay	F	5.72	pEC50	1900	nM	EC50	Eur J Med Chem (2018) 157: 198-228 [PMID:30096653]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]