lincomycin   Click here for help

GtoPdb Ligand ID: 10941

Synonyms: Bactramycin® | L-Mycin® | LCM | Lincocin® | Lincorex® | U 10,149A | U-10149
Approved drug PDB Ligand
lincomycin is an approved drug (FDA (1964))
Compound class: Synthetic organic
Comment: Lincomycin is a lincosamide antibiotic that has activity against Gram-positive and anaerobic bacteria [2]. It was isolated from the actinomycete Streptomyces lincolnensis. Pathogenic species of bacteria that are sensitive to lincomycin include Streptococcus, Staphylococcus, and Mycoplasma.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 8
Hydrogen bond donors 5
Rotatable bonds 8
Topological polar surface area 147.79
Molecular weight 406.21
XLogP 0.69
No. Lipinski's rules broken 0
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Canonical SMILES CCC[C@H]1CN([C@@H](C1)C(=O)N[C@@H]([C@H]1O[C@H](SC)[C@@H]([C@H]([C@H]1O)O)O)[C@H](O)C)C
Isomeric SMILES CCC[C@H]1CN([C@@H](C1)C(=O)N[C@@H]([C@H]1O[C@H](SC)[C@@H]([C@H]([C@H]1O)O)O)[C@H](O)C)C
InChI InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1964))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
1419 lincomycin
Synonyms Click here for help
Bactramycin® | L-Mycin® | LCM | Lincocin® | Lincorex® | U 10,149A | U-10149
Database Links Click here for help
BindingDB Ligand 50335522
CAS Registry No. 154-21-2 (source: WHO INN record)
ChEMBL Ligand CHEMBL1447
DrugBank Ligand DB01627
DrugCentral Ligand 1582
GtoPdb PubChem SID 405560382
PubChem CID 3000540
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