ChEMBL ligand: CHEMBL221542 (beta-Sitosterol, b-Sitosterol)
dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Human [ChEMBL: CHEMBL284] [GtoPdb: 1612] [UniProtKB: P27487] There should be some charts here, you may need to enable JavaScript!
DNA polymerase beta in Human [ChEMBL: CHEMBL2392] [GtoPdb: 3231] [UniProtKB: P06746] There should be some charts here, you may need to enable JavaScript!
Plasmodium falciparum [ChEMBL: CHEMBL364] There should be some charts here, you may need to enable JavaScript!
coagulation factor II, thrombin/Thrombin in Human [ChEMBL: CHEMBL204] [GtoPdb: 2362] [UniProtKB: P00734] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL284] [GtoPdb: 1612] [UniProtKB: P27487]
ChEMBL	Inhibition of human DPP4 using H-Gly-Pro-AMC peptide substrate assessed as increase in fluorescence for 20 mins by fluorimetric assay	B	4.54	pIC50	28840	nM	IC50	Medchemcomm (2011) 2: 471-477
DNA polymerase beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2392] [GtoPdb: 3231] [UniProtKB: P06746]
ChEMBL	Inhibition of DNA polymerase beta lyase activity by deoxyribose phosphate excision assay	B	4.58	pIC50	26300	nM	IC50	J Nat Prod (2003) 66: 1463-1465 [PMID:14640519]
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL	Antiplasmodial activity against Plasmodium falciparum W2	F	4.3	pIC50	>50000	nM	IC50	Bioorg Med Chem Lett (2013) 23: 3088-3095 [PMID:23562058]
ChEMBL	Antiplasmodial activity against Plasmodium falciparum D6	F	4.3	pIC50	>50000	nM	IC50	Bioorg Med Chem Lett (2013) 23: 3088-3095 [PMID:23562058]
coagulation factor II, thrombin/Thrombin in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL204] [GtoPdb: 2362] [UniProtKB: P00734]
ChEMBL	Uncompetitive inhibition of human thrombin using T1637 as substrate by Michaelis-Menten plot analysis	B	6.57	pKi	267.2	nM	Ki	J Nat Prod (2018) 81: 2521-2530 [PMID:30406661]
ChEMBL	Inhibition of thrombin in human platelet rich plasma assessed as reduction in thrombin-induced platelet aggregation after 5 mins	B	4.98	pIC50	10500	nM	IC50	J Nat Prod (2018) 81: 2521-2530 [PMID:30406661]
ChEMBL	Inhibition of thrombin in human washed platelets assessed as reduction in thrombin-induced platelet aggregation after 5 mins	B	5.04	pIC50	9200	nM	IC50	J Nat Prod (2018) 81: 2521-2530 [PMID:30406661]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]