cannabidiol [Ligand Id: 4150] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL190461 (BTX-1204, BTX-1503, (-)-cannabidiol, Cannabidiol, Cannabidiol solution, Cardiolrx, (-)-cbd, CBD, .delta.1(2)-trans-cannabidiol, Epidiolex, Epidyolex, GWP-42003, GWP42003, GWP-42003-P, GWP42003-P, (-)-trans-cannabidiol)
  • Acetylcholinesterase in Electrophorus electricus [ChEMBL: CHEMBL4078] [UniProtKB: O42275]
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  • α2B-adrenoceptor/Alpha-2b adrenergic receptor in Human [ChEMBL: CHEMBL1942] [GtoPdb: 26] [UniProtKB: P18089]
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  • α2C-adrenoceptor/Alpha-2c adrenergic receptor in Human [ChEMBL: CHEMBL1916] [GtoPdb: 27] [UniProtKB: P18825]
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  • Fatty acid amide hydrolase/Anandamide amidohydrolase in Rat [ChEMBL: CHEMBL3229] [GtoPdb: 1400] [UniProtKB: P97612]
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  • CB1 receptor/Cannabinoid CB1 receptor in Human [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
  • CB1 receptor/Cannabinoid CB1 receptor in Rat [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
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  • CB2 receptor/Cannabinoid CB2 receptor in Human [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
  • CB2 receptor/Cannabinoid CB2 receptor in Mouse [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936]
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  • δ receptor/Delta opioid receptor in Human [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
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  • D1 receptor/Dopamine D1 receptor in Human [ChEMBL: CHEMBL2056] [GtoPdb: 214] [UniProtKB: P21728]
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  • H3 receptor/Histamine H3 receptor in Human [ChEMBL: CHEMBL264] [GtoPdb: 264] [UniProtKB: Q9Y5N1]
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  • κ receptor/Kappa opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
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  • L-lactate dehydrogenase A chain in Human [ChEMBL: CHEMBL4835] [UniProtKB: P00338]
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  • μ receptor/Mu opioid receptor in Human [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
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  • N-Acylethanolamine acid amidase/N-acylsphingosine-amidohydrolase in Human [ChEMBL: CHEMBL4349] [GtoPdb: 1402] [UniProtKB: Q02083]
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  • Peroxisome proliferator-activated receptor-γ/Peroxisome proliferator-activated receptor gamma in Human [ChEMBL: CHEMBL235] [GtoPdb: 595] [UniProtKB: P37231]
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  • 5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908]
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  • 5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Rat [ChEMBL: CHEMBL322] [GtoPdb: 6] [UniProtKB: P14842]
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  • 5-HT2C receptor/Serotonin 2c (5-HT2c) receptor in Human [ChEMBL: CHEMBL225] [GtoPdb: 8] [UniProtKB: P28335]
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  • diacylglycerol lipase α/Sn1-specific diacylglycerol lipase alpha in Human [ChEMBL: CHEMBL5545] [GtoPdb: 1396] [UniProtKB: Q9Y4D2]
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  • TRPA1/Transient receptor potential cation channel subfamily A member 1 in Rat [ChEMBL: CHEMBL5160] [GtoPdb: 485] [UniProtKB: Q6RI86]
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  • TRPM8/Transient receptor potential cation channel subfamily M member 8 in Human [ChEMBL: CHEMBL1075319] [GtoPdb: 500] [UniProtKB: Q7Z2W7]
  • TRPM8/Transient receptor potential cation channel subfamily M member 8 in Rat [ChEMBL: CHEMBL5011] [GtoPdb: 500] [UniProtKB: Q8R455]
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  • TRPV2 in Human [GtoPdb: 508] [UniProtKB: Q9Y5S1]
  • TRPV2/Transient receptor potential cation channel subfamily V member 2 in Rat [ChEMBL: CHEMBL2863] [GtoPdb: 508] [UniProtKB: Q9WUD2]
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  • TRPV4/Transient receptor potential cation channel subfamily V member 4 in Rat [ChEMBL: CHEMBL2775] [GtoPdb: 510] [UniProtKB: Q9ERZ8]
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  • Cav1.2/Voltage-gated L-type calcium channel alpha-1C subunit in Rat [ChEMBL: CHEMBL3762] [GtoPdb: 529] [UniProtKB: P22002]
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  • GPR18 in Human [GtoPdb: 89] [UniProtKB: Q14330]
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  • TRPV3 in Rat [GtoPdb: 509]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Acetylcholinesterase in Electrophorus electricus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4078] [UniProtKB: O42275]
ChEMBL Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured after 20 mins by Ellman's method B 4.77 pIC50 17070 nM IC50 Eur J Med Chem (2021) 223: 113735-113735 [PMID:34371367]
α2B-adrenoceptor/Alpha-2b adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1942] [GtoPdb: 26] [UniProtKB: P18089]
ChEMBL Inhibition of alpha2B receptor (unknown origin) B 5.49 pKi 3200 nM Ki J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
α2C-adrenoceptor/Alpha-2c adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1916] [GtoPdb: 27] [UniProtKB: P18825]
ChEMBL Inhibition of alpha2C receptor (unknown origin) B 5.43 pKi 3700 nM Ki J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
Fatty acid amide hydrolase/Anandamide amidohydrolase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3229] [GtoPdb: 1400] [UniProtKB: P97612]
ChEMBL Inhibition of FAAH in rat brain membranes using [14C]-AEA as substrate measured after 30 mins by scintillation counting method B 4.27 pIC50 53200 nM IC50 J Nat Prod (2019) 82: 636-646 [PMID:30816712]
CB1 receptor/Cannabinoid CB1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
ChEMBL Binding affinity towards cloned human Cannabinoid receptor 1 B 3.64 pKi 3.64 nM Log Ki J Med Chem (2000) 43: 2300-2309 [PMID:10882356]
ChEMBL Binding affinity to human CB1 receptor B 5.36 pKi 4350 nM Ki J Med Chem (2013) 56: 8224-8256 [PMID:23865723]
ChEMBL Displacement of [3H]CP-55,940 from human CB1 receptor expressed in CHO cells incubated for 1 hr by liquid scintillation spectrometry B 5.36 pKi 4350 nM Ki J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
ChEMBL Displacement of [3H]CP-55940 from human cannabinoid CB1 receptor expressed in CHO cells B 5.62 pKi 2400 nM Ki J Med Chem (2010) 53: 4332-4353 [PMID:20218623]
ChEMBL Displacement of [3H]-CP55940 from recombinant human CB1 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 mins by scintillation counting method B 5.84 pKi 1459 nM Ki J Nat Prod (2019) 82: 636-646 [PMID:30816712]
CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
ChEMBL Displacement of [3H]HU243 from CB1 receptor in Sabra rat brain B 5 pKi >10000 nM Ki J Med Chem (2006) 49: 1113-1117 [PMID:16451075]
ChEMBL Displacement of [3H]-HU-243 from CB1 receptor in Sabra rat brain synaptosomes after 90 mins B 5 pKi >10000 nM Ki ACS Med Chem Lett (2016) 7: 424-428 [PMID:27096053]
ChEMBL Displacement of [3H]CP55940 from rat brain membrane CB1 receptor assessed as inhibition constant incubated for 90 mins B 5 pKi >10000 nM Ki Eur J Med Chem (2020) 192: 112163-112163 [PMID:32109623]
ChEMBL Binding affinity for Cannabinoid receptor 1 by the ability to displace radiolabeled CP-55940 from purified rat forebrain synaptosomes B 5.9 pKi 1265 nM Ki Bioorg Med Chem Lett (2002) 12: 3583-3586 [PMID:12443781]
CB2 receptor/Cannabinoid CB2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
ChEMBL Binding affinity towards cloned human cannabinoid receptor 2 B 3.46 pKi 3.46 nM Log Ki J Med Chem (2000) 43: 2300-2309 [PMID:10882356]
ChEMBL Displacement of [3H]CP-55940 from human cannabinoid CB2 receptor expressed in CHO cells B 5 pKi 10000 nM Ki J Med Chem (2010) 53: 4332-4353 [PMID:20218623]
ChEMBL Binding affinity to human CB2 receptor B 5.54 pKi 2860 nM Ki J Med Chem (2013) 56: 8224-8256 [PMID:23865723]
ChEMBL Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cells incubated for 1 hr by liquid scintillation spectrometry B 5.54 pKi 2860 nM Ki J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
ChEMBL Displacement of [3H]-CP55940 from recombinant human CB2 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 mins by scintillation counting method B 6.43 pKi 372 nM Ki J Nat Prod (2019) 82: 636-646 [PMID:30816712]
ChEMBL Partial agonist activity at wild type CB2 receptor (unknown origin) expressed in HEK293T assessed as increase in picometer shifts of reflected light wavelengths in presence of JWH-133 by DMR assay F 6.2 pEC50 630.96 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 V361.35M mutant (unknown origin) expressed in HEK293T assessed as increase in picometer shifts of reflected light wavelengths in presence of JWH-133 by DMR assay F 6.2 pEC50 630.96 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 V1133.32M mutant (unknown origin) expressed in HEK293T assessed as increase in picometer shifts of reflected light wavelengths by DMR assay F 6.2 pEC50 630.96 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at wild type CB2 receptor (unknown origin) expressed in HEK293T assessed as increase in picometer shifts of reflected light wavelengths by DMR assay F 6.3 pEC50 501.19 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 V1133.32M mutant (unknown origin) expressed in HEK293T assessed as increase in picometer shifts of reflected light wavelengths in presence of JWH-133 by DMR assay F 6.4 pEC50 398.11 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Positive allosteric modulation of JWH-133-induced agonist activity at wild type CB2 receptor (unknown origin) stably expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP levels preincubated for 15 mins followed by forskolin addition incubated for 15 mins by HTRF assay F 6.6 pEC50 251.19 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at wild type CB2 receptor (unknown origin) stably expressed in HEK293T assessed as decrease in forskolin induced cAMP level preincubated for 15 mins followed by forskolin addition incubated for 15 mins by HTRF assay F 7.3 pEC50 50.12 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at wild type CB2 receptor (unknown origin) stably expressed in HEK293T assessed as decrease in forskolin induced cAMP level preincubated for 15 mins followed by forskolin addition incubated for 15 mins in presence of JWH-133 by HTRF assay F 7.3 pEC50 50.12 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 V361.35M mutant (unknown origin) expressed in HEK293T assessed as increase in ERK1/2 phosphorylation incubated for 7 mins in presence of JWH-133 by AlphaScreenSureFire method F 7.4 pEC50 39.81 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 S2857.39L mutant (unknown origin) stably expressed in HEK293T assessed as decrease in forskolin induced cAMP level preincubated for 15 mins followed by forskolin addition incubated for 15 mins in presence of JWH-133 by HTRF assay F 7.4 pEC50 39.81 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 V1133.32M mutant (unknown origin) expressed in HEK293T assessed as increase in ERK1/2 phosphorylation incubated for 7 mins in presence of JWH-133 by AlphaScreenSureFire method F 7.4 pEC50 39.81 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 V1133.32M mutant (unknown origin) stably expressed in HEK293T assessed as decrease in forskolin induced cAMP level preincubated for 15 mins followed by forskolin addition incubated for 15 mins by HTRF assay F 7.4 pEC50 39.81 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 S2857.39L mutant (unknown origin) expressed in HEK293T assessed as increase in ERK1/2 phosphorylation incubated for 7 mins in presence of JWH-133 by AlphaScreenSureFire method F 7.5 pEC50 31.62 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 V1133.32M mutant (unknown origin) stably expressed in HEK293T assessed as decrease in forskolin induced cAMP level preincubated for 15 mins followed by forskolin addition incubated for 15 mins in presence of JWH-133 by HTRF assay F 7.6 pEC50 25.12 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 V361.35M mutant (unknown origin) stably expressed in HEK293T assessed as decrease in forskolin induced cAMP level preincubated for 15 mins followed by forskolin addition incubated for 15 mins in presence of JWH-133 by HTRF assay F 7.8 pEC50 15.85 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at wild type CB2 receptor (unknown origin) expressed in HEK293T assessed as increase in ERK1/2 phosphorylation incubated for 7 mins by AlphaScreenSureFire method F 7.9 pEC50 12.59 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 V1133.32M mutant (unknown origin) expressed in HEK293T assessed as increase in ERK1/2 phosphorylation incubated for 7 mins by AlphaScreenSureFire method F 7.9 pEC50 12.59 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 A2827.36M mutant (unknown origin) expressed in HEK293T assessed as increase in ERK1/2 phosphorylation incubated for 7 mins in presence of JWH-133 by AlphaScreenSureFire method F 7.9 pEC50 12.59 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at CBR2 A2827.36M mutant (unknown origin) stably expressed in HEK293T assessed as decrease in forskolin induced cAMP level preincubated for 15 mins followed by forskolin addition incubated for 15 mins in presence of JWH-133 by HTRF assay F 8.1 pEC50 7.94 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
ChEMBL Partial agonist activity at wild type CB2 receptor (unknown origin) expressed in HEK293T assessed as increase in ERK1/2 phosphorylation incubated for 7 mins in presence of JWH-133 by AlphaScreenSureFire method F 8.1 pEC50 7.94 nM EC50 J Med Chem (2021) 64: 9354-9364 [PMID:34161090]
CB2 receptor/Cannabinoid CB2 receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936]
ChEMBL Binding affinity for Cannabinoid receptor 2 by the ability to displace radiolabeled CP-55940 from mouse spleen synaptosomes B 6.64 pKi 230 nM Ki Bioorg Med Chem Lett (2002) 12: 3583-3586 [PMID:12443781]
Caspase 1/Caspase-1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4801] [GtoPdb: 1617] [UniProtKB: P29466]
ChEMBL Binding affinity to recombinant human caspase-1 assessed as dissociation constant measured after 90 sec by SPR method B 7.73 pKd 18.8 nM Kd J Nat Prod (2021) 84: 1563-1572 [PMID:33955754]
Cholinesterase in Equus caballus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5763] [UniProtKB: P81908]
ChEMBL Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured after 20 mins by Ellman's method B 6.17 pIC50 670 nM IC50 Eur J Med Chem (2021) 223: 113735-113735 [PMID:34371367]
δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
ChEMBL Inhibition of delta-type opioid receptor receptor (unknown origin) B 5.19 pKi 6400 nM Ki J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
D1 receptor/Dopamine D1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2056] [GtoPdb: 214] [UniProtKB: P21728]
ChEMBL Inhibition of D1 dopamine receptor (unknown origin) B 5.57 pKi 2700 nM Ki J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
GPR55/G-protein coupled receptor 55 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075322] [GtoPdb: 109] [UniProtKB: Q9Y2T6]
GtoPdb - - 6.46 pIC50 350 nM IC50 Br J Pharmacol (2007) 152: 1092-101 [PMID:17876302];
Pharmacol Rev (2010) 62: 588-631 [PMID:21079038]
ChEMBL Binding affinity to GPR55 B 6.35 pEC50 445 nM EC50 J Med Chem (2010) 53: 4332-4353 [PMID:20218623]
Heat sensitive channel TRPV3 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3879847] [UniProtKB: Q4QYD9]
ChEMBL Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced Ca2+ response preincubated for 5 mins followed by thymol addition by Fluo-4AM dye based fluorescence assay B 6.12 pIC50 750 nM IC50 J Nat Prod (2020) 83: 2727-2736 [PMID:32880179]
ChEMBL Agonist activity at rat TRPV3 stably transfected in HEK293 cells assessed as increase in calcium influx in presence of ionomycin by Fluo-4-AM dye based spectrofluorimetric method B 6.29 pEC50 510 nM EC50 J Nat Prod (2020) 83: 2727-2736 [PMID:32880179]
Hemozoin in Plasmodium falciparum (target type: MACROMOLECULE) [ChEMBL: CHEMBL613898]
ChEMBL Inhibition of Beta-hematin in Plasmodium falciparum cells assessed as hemozoin formation after 32 hrs by NP40 detergent-mediated assay B 4.29 pIC50 51100 nM IC50 Bioorg Med Chem Lett (2021) 54: 128442-128442 [PMID:34763083]
H3 receptor/Histamine H3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL264] [GtoPdb: 264] [UniProtKB: Q9Y5N1]
ChEMBL Inhibition of histamine H3 receptor (unknown origin) B 5.51 pKi 3100 nM Ki J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
κ receptor/Kappa opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
ChEMBL Inhibition of kappa-type opioid receptor (unknown origin) B 5.64 pKi 2300 nM Ki J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
L-lactate dehydrogenase A chain in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4835] [UniProtKB: P00338]
ChEMBL Non-competitive inhibition of human LDHA assessed as reduction in lactate production using pyruvate as substrate in presence of NADH by Lineweaver-Burk plot analysis B 4.62 pKi 24000 nM Ki J Nat Prod (2021) 84: 1469-1477 [PMID:33887133]
μ receptor/Mu opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
ChEMBL Inhibition of mu-type opioid receptor (unknown origin) B 5.89 pKi 1300 nM Ki J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
N-Acylethanolamine acid amidase/N-acylsphingosine-amidohydrolase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4349] [GtoPdb: 1402] [UniProtKB: Q02083]
ChEMBL Inhibition of recombinant human NAAA expressed in HEK293 cells using [14C]-N-palmitoylethanolamine as substrate measured after 30 mins by beta-counting method B 4 pIC50 >100000 nM IC50 J Nat Prod (2019) 82: 636-646 [PMID:30816712]
Peroxisome proliferator-activated receptor-γ/Peroxisome proliferator-activated receptor gamma in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL235] [GtoPdb: 595] [UniProtKB: P37231]
ChEMBL Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6 hrs by dual luciferase reporter gene assay B 4.6 pEC50 >25000 nM EC50 J Nat Prod (2020) 83: 1711-1715 [PMID:32315173]
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum NF54 F 5.39 pIC50 4100 nM IC50 Bioorg Med Chem Lett (2021) 54: 128442-128442 [PMID:34763083]
5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908]
ChEMBL Displacement of [3H]8-OH-DPAT from human 5-HT1a receptor expressed in CHO cells incubated for 30 mins by liquid scintillation counting method B 5.1 pEC50 8000 nM EC50 J Med Chem (2020) 63: 12137-12155 [PMID:32804502]
5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL322] [GtoPdb: 6] [UniProtKB: P14842]
ChEMBL Displacement of [3H] ketanserin from rat 5-HT2aR expressed in mouse NIH/3T3 cells incubated for 30 mins by liquid scintillation counting method