garcinoic acid [Ligand Id: 10734] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Pregnane X receptor in Human [GtoPdb: 606] [UniProtKB: O75469] | ||||||||
| GtoPdb | Binding affinity to hPXR ligand binding domain determined using an isothermic titration calorimetry (ITC) assay. | - | 6.48 | pKd | 330 | nM | Kd | J Med Chem (2020) 63: 3701-3712 [PMID:32160459] |
| GtoPdb | Agonist activity determined using a proprietary AlphaScreen method. | - | 5.89 | pEC50 | 1300 | nM | EC50 | J Med Chem (2020) 63: 3701-3712 [PMID:32160459] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
