compound 5 [PMID: 10869194] [Ligand Id: 8843] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL503874
  • PLCγ1/Phospholipase C-gamma-1 in Human [ChEMBL: CHEMBL3964] [GtoPdb: 1407] [UniProtKB: P19174]
  • PLCγ1 in Bovine [GtoPdb: 1407]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
PLCγ1/Phospholipase C-gamma-1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3964] [GtoPdb: 1407] [UniProtKB: P19174]
ChEMBL Inhibition of PLCgamma1 B 5.02 pIC50 9500 nM IC50 J. Nat. Prod. (2000) 63: 753-756 [PMID:10869194]
PLCγ1 in Bovine [GtoPdb: 1407]
GtoPdb - - 5.02 pIC50 9500 nM IC50 J Nat Prod (2000) 63: 753-6 [PMID:10869194]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]