compound 5 [PMID: 10869194] [Ligand Id: 8843] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL503874
  • PLCγ1/Phospholipase C-gamma-1 in Human [ChEMBL: CHEMBL3964] [GtoPdb: 1407] [UniProtKB: P19174]
  • PLCγ1 in Bovine [GtoPdb: 1407]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
PLCγ1/Phospholipase C-gamma-1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3964] [GtoPdb: 1407] [UniProtKB: P19174]
ChEMBL Inhibition of PLCgamma1 B 5.02 pIC50 9500 nM IC50 J Nat Prod (2000) 63: 753-756 [PMID:10869194]
PLCγ1 in Bovine [GtoPdb: 1407]
GtoPdb - - 5.02 pIC50 9500 nM IC50 J Nat Prod (2000) 63: 753-6 [PMID:10869194]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]