abscisic acid [Ligand Id: 10362] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL379808 ((+/-)-Abscisic Acid, Abscisic Acid)
  • TAS2R4 in Human [GtoPdb: 661] [UniProtKB: Q9NYW5]
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  • LanC like 2 in Human [GtoPdb: 3082] [UniProtKB: Q9NS86]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TAS2R4 in Human [GtoPdb: 661] [UniProtKB: Q9NYW5]
GtoPdb - - 4.46 pIC50 34400 nM IC50 Biochemistry (2015) 54: 2622-31 [PMID:25844797]
LanC like 2 in Human [GtoPdb: 3082] [UniProtKB: Q9NS86]
GtoPdb High affinity binding site identified using Scatchard plot analysis of [3H]ABA binding to human granulocyte plasma membranes. - 7.96 pKd 11 nM Kd Proc Natl Acad Sci USA (2007) 104: 5759-64 [PMID:17389374]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]