Synonyms: Novo29
Compound class:
Natural product
Comment: Clovibactin is a natural peptide isolated from the uncultured soil-dwelling bacterium Eleftheria terrae ssp. carolina [3]. It is related in structure to teixobactin and is active against Gram-positive bacteria [2]. The chemical structure is one of those claimed in patent WO2018187173 filed by NovoBiotic Pharmaceuticals [1]. It is in preclinical development as a potential treatment for a wide range of bacterial infections caused by Gram-positive pathogens.
Functionally, clovibactin disrupts bacterial cell wall synthesis by binding to the pyrophosphate of multiple essential peptidoglycan precursors (C55PP, lipid II, and lipid IIIWTA) [3]. |
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Classification ![]() |
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Compound class | Natural product |
Synonyms ![]() |
Novo29 |
Database Links ![]() |
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Specialist databases | |
Antibiotic DB
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Clovibactin |
Other databases | |
CAS Registry No. | 2247194-77-8 (source: Scifinder) |
GtoPdb PubChem SID | 491299862 |
PubChem CID | 146342518 |
Search Google for chemical match using the InChIKey | SMQAHGKBWXPEHB-HHHSQLJLSA-N |
Search Google for chemicals with the same backbone | SMQAHGKBWXPEHB |
UniChem Compound Search for chemical match using the InChIKey | SMQAHGKBWXPEHB-HHHSQLJLSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | SMQAHGKBWXPEHB-HHHSQLJLSA-N |