aplithianine A [Ligand Id: 13089] activity data from GtoPdb

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  • protein kinase, cAMP-dependent, catalytic, alpha subunit in Human [GtoPdb: 1476] [UniProtKB: P17612]
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  • protein kinase C theta in Human [GtoPdb: 1488] [UniProtKB: Q04759]
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  • Protein kinase G (PKG) 1 in Human [GtoPdb: 1492] [UniProtKB: Q13976]
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  • Protein kinase G (PKG) 2 in Human [GtoPdb: 1493] [UniProtKB: Q13237]
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  • serine/threonine kinase 39 in Human [GtoPdb: 2224] [UniProtKB: Q9UEW8]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
protein kinase, cAMP-dependent, catalytic, alpha subunit in Human [GtoPdb: 1476] [UniProtKB: P17612]
GtoPdb - - 7.08 pIC50 84 nM IC50 J Nat Prod (2023) 86: 2283-2293 [PMID:37843072]
protein kinase C theta in Human [GtoPdb: 1488] [UniProtKB: Q04759]
GtoPdb - - 7.44 pIC50 36 nM IC50 J Nat Prod (2023) 86: 2283-2293 [PMID:37843072]
Protein kinase G (PKG) 1 in Human [GtoPdb: 1492] [UniProtKB: Q13976]
GtoPdb Inhibition of PGK1α - 7.96 pIC50 11 nM IC50 J Nat Prod (2023) 86: 2283-2293 [PMID:37843072]
Protein kinase G (PKG) 2 in Human [GtoPdb: 1493] [UniProtKB: Q13237]
GtoPdb - - 7.47 pIC50 34 nM IC50 J Nat Prod (2023) 86: 2283-2293 [PMID:37843072]
serine/threonine kinase 39 in Human [GtoPdb: 2224] [UniProtKB: Q9UEW8]
GtoPdb - - 7.46 pIC50 35 nM IC50 J Nat Prod (2023) 86: 2283-2293 [PMID:37843072]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.