salvianolic acid B [Ligand Id: 13515] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1615434
  • platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
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  • lysine demethylase 1A in Human [GtoPdb: 2669] [UniProtKB: O60341]
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  • Piezo1 in Human [GtoPdb: 2945] [UniProtKB: Q92508]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
GtoPdb Binding affinity determined by surface plasmon resonance analysis - 5.21 pKd 6150 nM Kd Int Immunopharmacol (2023) 122: 110550 [PMID:37451016]
lysine demethylase 1A in Human [GtoPdb: 2669] [UniProtKB: O60341]
GtoPdb - - 6.96 pIC50 110 nM IC50 Talanta (2020) 206: 120195 [PMID:31514831]
Piezo1 in Human [GtoPdb: 2945] [UniProtKB: Q92508]
GtoPdb - - 5.9 pIC50 - - - Br J Pharmacol (2022) 179: 3778-3814 [PMID:35194776]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]