ChEMBL ligand: CHEMBL4105357
TAS2R16/Taste receptor type 2 member 16 in Human [ChEMBL: CHEMBL3309106] [GtoPdb: 669] [UniProtKB: Q9NYV7] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
TAS2R16/Taste receptor type 2 member 16 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3309106] [GtoPdb: 669] [UniProtKB: Q9NYV7]
GtoPdb	-	-	2.96	pEC50	1100000	nM	EC50	Nat Genet (2002) 32: 397-401 [PMID:12379855]
ChEMBL	Activation of full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio in presence of (E)-4-(2,2,3-trimethylcyclopent-3-enyl)but-2-enoic acid by Fluo-4 dye based FLIPR assay	F	6.6	pEC50	250	nM	EC50	US-8187822-B2. Methods to identify modulators (2012)
ChEMBL	Activation of full-length human TAS2R16 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio by Fluo-4 dye based FLIPR assay	F	6.68	pEC50	210	nM	EC50	US-8187822-B2. Methods to identify modulators (2012)

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]