tonantzitlolone

Ligand id: 10287

Name: tonantzitlolone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 102.29
Molecular weight 464.28
XLogP 3.08
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Natural product or derivative
IUPAC Name
[(1R,2S,3R,6S,8Z,10S,12R,14R,15R)-1,2-dihydroxy-3,7,7,10,14-pentamethyl-11-oxo-16,17-dioxatricyclo[10.3.1.13,6]heptadec-8-en-15-yl] (E)-3-methylpent-2-enoate
Comments
Tonantzitlolone is a natural product with effects similar to (-)-englerin A. Like (-)-englerin A the effects of tonantzitlolone appear to mediated by activation of cation flux via TRPC ion channels, principally the TRPC1/4/5 channel subtypes [1].
Database Links
CAS Registry No. 845811-30-5 (source: PubChem)
GtoPdb PubChem SID 381744968
PubChem CID 102216630
Search Google for chemical match using the InChIKey YMEAIOHYSIGDJY-VDLZEVDKSA-N
Search Google for chemicals with the same backbone YMEAIOHYSIGDJY
Search UniChem for chemical match using the InChIKey YMEAIOHYSIGDJY-VDLZEVDKSA-N
Search UniChem for chemicals with the same backbone YMEAIOHYSIGDJY