ChEMBL ligand: CHEMBL190
A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542] A1 receptor in Rat [GtoPdb: 18] [UniProtKB: P25099] There should be some charts here, you may need to enable JavaScript!
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274] A2A receptor in Rat [GtoPdb: 19] [UniProtKB: P30543] There should be some charts here, you may need to enable JavaScript!
A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275] A2B receptor in Mouse [GtoPdb: 20] [UniProtKB: Q60614] There should be some charts here, you may need to enable JavaScript!
A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8] A3 receptor in Rat [GtoPdb: 21] [UniProtKB: P28647] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
GtoPdb	-	-	5.2	pKi	-	-	-	J Biol Chem (1994) 269: 32077-84 [PMID:7798201]; Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 1-9 [PMID:9459566]; Biochem Pharmacol (2005) 70: 1601-12 [PMID:16219300]; Biochem Pharmacol (2001) 62: 1163-73 [PMID:11705449]
A1 receptor in Rat [GtoPdb: 18] [UniProtKB: P25099]
GtoPdb	-	-	5.06	pKi	8740	nM	Ki	Drug Dev Res (1999) : 45-53; J Med Chem (1993) 36: 3341-9 [PMID:8230124]
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
GtoPdb	-	-	5.8	pKi	-	-	-	Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 1-9 [PMID:9459566]; Biochem Pharmacol (2005) 70: 1601-12 [PMID:16219300]; Br J Pharmacol (1997) 121: 353-60 [PMID:9179373]; Drug Dev Res (1999) : 45-53
A2A receptor in Rat [GtoPdb: 19] [UniProtKB: P30543]
GtoPdb	-	-	4.66	pKi	22000	nM	Ki	Drug Dev Res (1999) : 45-53; J Med Chem (1993) 36: 3341-9 [PMID:8230124]
A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
GtoPdb	-	-	5.04	pKi	9070	nM	Ki	Biochem Pharmacol (2005) 70: 1601-12 [PMID:16219300]; Biochem Pharmacol (2001) 62: 1163-73 [PMID:11705449]; J Med Chem (2002) 45: 2131-8 [PMID:12014951]; Purinergic Signal (2006) 2: 559-71 [PMID:18404493]
A2B receptor in Mouse [GtoPdb: 20] [UniProtKB: Q60614]
GtoPdb	-	-	5.25	pKi	5630	nM	Ki	J Pharmacol Exp Ther (2009) 329: 2-13 [PMID:19141710]
A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8]
GtoPdb	-	-	4.65	pKi	22300	nM	Ki	Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 1-9 [PMID:9459566]; Drug Dev Res (1999) : 45-53
A3 receptor in Rat [GtoPdb: 21] [UniProtKB: P28647]
GtoPdb	-	-	4.07	pKi	85000	nM	Ki	Mol Pharmacol (1994) 45: 1101-11 [PMID:8022403]; Bioconjug Chem (1995) 6: 255-63 [PMID:7632796]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]