Classification
Compound class	Natural product or derivative

IUPAC Name

(3R,5aS,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-3,10a-bis(methylsulfanyl)-1H,2H,3H,4H,5aH,6H,10H,10aH-piperazino[1,2-a]indole-1,4-dione

Synonyms

AC1L4YI4 | bis(methylthio)gliotoxin | dimethylgliotoxin | FR 49175

Comments

FR-49175 is a toxic metabolite with anthiphagocytic and immunosuppressive properties synthesised by fungi such as Aspergillus fumigatus. It is an analog of a gliotoxin known to inhibit PAF-induced platelet aggregation.

Database Links
CAS Registry No.	74149-38-5 (source: Scifinder)
ChEMBL Ligand	CHEMBL1088981
GtoPdb PubChem SID	178100262
PubChem CID	194564
Search Google for chemical match using the InChIKey	OVBAGMZLGLXSBN-UOVKNHIHSA-N
Search Google for chemicals with the same backbone	OVBAGMZLGLXSBN
Search UniChem for chemical match using the InChIKey	OVBAGMZLGLXSBN-UOVKNHIHSA-N
Search UniChem for chemicals with the same backbone	OVBAGMZLGLXSBN