GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.
Synonyms: AC1L4YI4 | bis(methylthio)gliotoxin | dimethylgliotoxin | FR 49175
Compound class:
Natural product
Comment: FR-49175 is a toxic metabolite with anthiphagocytic and immunosuppressive properties synthesised by fungi such as Aspergillus fumigatus. It is an analog of a gliotoxin known to inhibit PAF-induced platelet aggregation.
|
|
Classification ![]() |
|
Compound class | Natural product |
IUPAC Name ![]() |
(3R,5aS,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-3,10a-bis(methylsulfanyl)-1H,2H,3H,4H,5aH,6H,10H,10aH-piperazino[1,2-a]indole-1,4-dione |
Synonyms ![]() |
AC1L4YI4 | bis(methylthio)gliotoxin | dimethylgliotoxin | FR 49175 |
Database Links ![]() |
|
CAS Registry No. | 74149-38-5 (source: Scifinder) |
ChEMBL Ligand | CHEMBL1088981 |
GtoPdb PubChem SID | 178100262 |
PubChem CID | 194564 |
Search Google for chemical match using the InChIKey | OVBAGMZLGLXSBN-UOVKNHIHSA-N |
Search Google for chemicals with the same backbone | OVBAGMZLGLXSBN |
UniChem Compound Search for chemical match using the InChIKey | OVBAGMZLGLXSBN-UOVKNHIHSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | OVBAGMZLGLXSBN-UOVKNHIHSA-N |